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ICD-10/G72.81

G72.81 ICD-10-CM Code: Critical illness myopathy

G72.81 is the authoritative medical code for Critical illness myopathy. This classification is used in medical billing and clinical recording to specify the clinical criteria for critical illness myopathy (ICD-10-CM G72.81), ensuring healthcare documentation aligns with current federal coding standards.

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0 (FY2026), Appendix B.

  • MS-DRG 091 — OTHER DISORDERS OF NERVOUS SYSTEM WITH MCC (MDC 01)
  • MS-DRG 092 — OTHER DISORDERS OF NERVOUS SYSTEM WITH CC (MDC 01)
  • MS-DRG 093 — OTHER DISORDERS OF NERVOUS SYSTEM WITHOUT CC/MCC (MDC 01)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Code Set: Valid FY2026 and FY2027. FY2026 took effect October 1, 2025.

Official Registry Overview & Definition

Critical illness myopathy is a billable ICD-10-CM diagnosis code (G72.81). Inclusion terms: Acute necrotizing myopathy; Acute quadriplegic myopathy; Intensive care (ICU) myopathy; Myopathy of critical illness. Excludes1 (not coded here): arthrogryposis multiplex congenita (Q74.3); dermatopolymyositis (M33.-); ischemic infarction of muscle (M62.2-); myositis (M60.-); polymyositis (M33.2.-).

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for G72.81 in the official ICD-10-CM tabular list.

Inclusion Terms

Alternative terms the tabular list files under this code.

  • Acute necrotizing myopathy
  • Acute quadriplegic myopathy
  • Intensive care (ICU) myopathy
  • Myopathy of critical illness

Excludes1 — Not Coded Here

Conditions that can never be reported with this code; the two are mutually exclusive.

  • arthrogryposis multiplex congenita (Q74.3)
  • dermatopolymyositis (M33.-)
  • ischemic infarction of muscle (M62.2-)
  • myositis (M60.-)
  • polymyositis (M33.2.-)

Frequently Asked Questions (FAQ) & Clinical Guidance

What can't be coded together with G72.81?

Per official ICD-10-CM Excludes1 instructions, G72.81 must not be reported together with: arthrogryposis multiplex congenita (Q74.3); dermatopolymyositis (M33.-); ischemic infarction of muscle (M62.2-); myositis (M60.-).

What conditions are included under G72.81?

Critical illness myopathy includes: Acute necrotizing myopathy; Acute quadriplegic myopathy; Intensive care (ICU) myopathy; Myopathy of critical illness.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to G72.81 in its code family, with their registry titles.

  • G72.0 — Drug-induced myopathy
  • G72.1 — Alcoholic myopathy
  • G72.2 — Myopathy due to other toxic agents
  • G72.3 — Periodic paralysis
  • G72.4 — Inflammatory and immune myopathies, not elsewhere classified
  • G72.41 — Inclusion body myositis [IBM]
  • G72.49 — Other inflammatory and immune myopathies, not elsewhere classified
  • G72.8 — Other specified myopathies
  • G72.89 — Other specified myopathies
  • G72.9 — Myopathy, unspecified

View all codes in the G72 family

Indexed Clinical Terms (5)

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.

  • Myopathy, acute, necrotizing
  • Myopathy, acute, quadriplegic
  • Myopathy, critical illness
  • Myopathy, intensive care (ICU)
  • Myopathy, of critical illness