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O75.3 ICD-10-CM Code: Other infection during labor

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Tabular directives
1 inclusion term · 2 Excludes2 · 1 use-additional code

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43, Appendix B.

  • MS-DRG 817 — OTHER ANTEPARTUM DIAGNOSES WITH O.R. PROCEDURES WITH MCC (MDC 14)
  • MS-DRG 818 — OTHER ANTEPARTUM DIAGNOSES WITH O.R. PROCEDURES WITH CC (MDC 14)
  • MS-DRG 819 — OTHER ANTEPARTUM DIAGNOSES WITH O.R. PROCEDURES WITHOUT CC/MCC (MDC 14)
  • MS-DRG 831 — OTHER ANTEPARTUM DIAGNOSES WITHOUT O.R. PROCEDURES WITH MCC (MDC 14)
  • MS-DRG 832 — OTHER ANTEPARTUM DIAGNOSES WITHOUT O.R. PROCEDURES WITH CC (MDC 14)
  • MS-DRG 833 — OTHER ANTEPARTUM DIAGNOSES WITHOUT O.R. PROCEDURES WITHOUT CC/MCC (MDC 14)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for O75.3 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025

Notes without a marker are published on O75.3 itself; “inherited from” names the category or block whose note applies here.

Inclusion Terms

Alternative terms the tabular list files under this code.

  • Sepsis during labor

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Source: inherited from O75

Use Additional Code

Supplementary codes the tabular list directs you to add.

  • Use additional code (B95-B97), to identify infectious agent

Coder workflow for O75.3

MedCoder structured workflow — derived from this code’s own official record

Before you code O75.3

  1. “Other” (NEC) means the condition is specified in the record but no dedicated code captures it. Confirm the documented form is not one a sibling code names before settling on O75.3; if the record states no specifics at all, the unspecified sibling applies instead. “Other” codes are for documented conditions the classification gives no specific code; “unspecified” codes are for records lacking the detail (Guidelines I.A.9.a, I.A.9.b).

    ReviewO75.0, O75.1, O75.5

    See the relationships section · Guide: Other vs unspecified (NEC vs NOS) →

  2. Confirm the condition is documented as complicating the pregnancy, childbirth, or the puerperium, and check the trimester where the code carries one and the fetus character where the category requires it. Chapter 15 codes belong on the maternal record only and take sequencing priority over codes from other chapters. It is the provider’s responsibility to state that a condition is not affecting the pregnancy; the trimester is assigned from the documentation (Guidelines I.C.15.a, I.C.15.a.1, I.C.15.a.3).

    Guide: How to choose an ICD-10-CM code →

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
Trimester
Assigned from the documented trimester at the encounter, or the trimester in which the condition developed for inpatient stays (Guidelines I.C.15.a.3).
The conditions the Use Additional Code note names
Reported with this code when documented; a conditional instruction (“if applicable”, “if known”) applies only when the record supports it.
Any detail beyond this code’s title
What the record states that a more specific sibling code would capture — or its absence, which itself supports the unspecified code.

Official instructions as workflow

  • Excludes2 — not part of O75.3(2 notes)

    Coding workflow: The conditions named in this note are not included in O75.3. When the record documents both, both may be reported; the note is a boundary, not a prohibition.

    CompareO86, O85

    See the official tabular notes · Guidelines I.A.12.b

  • Use Additional Code — after identifying O75.3(1 note)

    Coding workflow: Check whether the documentation supports the additional code(s) the note names, and report them with O75.3 when it does. Where the instruction is conditional (“if applicable”, “if known”), it applies only when the record documents the condition.

    See the official tabular notes · Guidelines I.A.13

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Documentation: A condition the Use Additional Code note names is documented.

Coding question: Is a second code reported with O75.3?

Path: Review the Use Additional Code note and the code it names.

Reason: The additional code is reported when the record documents the condition; a conditional instruction applies only when its condition is met (Guidelines I.A.13).

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Code Overview

Other infection during labor is a billable ICD-10-CM diagnosis code (O75.3).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Indexed Clinical Terms (2)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Verify Before Coding

  • Age-restricted: the Medicare Code Editor lists this as a maternity (age 9-64) diagnosis; other ages are presumed incorrect.
  • MCC as a secondary diagnosis (FY2026). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name O75.3 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 9 Excludes1 notes: N70 — Salpingitis and oophoritis, N70-N77 — Inflammatory diseases of female pelvic organs (N70-N77), N71 — Inflammatory disease of uterus, except cervix, N72 — Inflammatory disease of cervix uteri, N73 — Other female pelvic inflammatory diseases, N74 — Female pelvic inflammatory disorders in diseases classified elsewhere, N75 — Diseases of Bartholin's gland, N76 — Other inflammation of vagina and vulva, N77 — Vulvovaginal ulceration and inflammation in diseases classified elsewhere.

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 12 Excludes2 notes across 2 chapters: N30 — Cystitis, N30-N39 — Other diseases of the urinary system (N30-N39), N31 — Neuromuscular dysfunction of bladder, not elsewhere classified, N32 — Other disorders of bladder, N33 — Bladder disorders in diseases classified elsewhere, N34 — Urethritis and urethral syndrome, N35 — Urethral stricture, N36 — Other disorders of urethra, N37 — Urethral disorders in diseases classified elsewhere, N39 — Other disorders of urinary system, O85 — Puerperal sepsis, O86 — Other puerperal infections.

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

Referenced by 2 Code First instructions: A40 — Streptococcal sepsis, A41 — Other sepsis.

Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

FY2026 MS-DRG: MCC — Major Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 221 clinically related codes on its CMS exclusion list.

Named in the grouper logic of 6 MS-DRGs: DRG 817 (MDC 14), DRG 818 (MDC 14), DRG 819 (MDC 14), DRG 831 (MDC 14), DRG 832 (MDC 14), DRG 833 (MDC 14).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):PRG023 — Complications specified during childbirth (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical process (MS-DRG)

Acts as MCC — raises the severity of other admissions. CMS groups these diagnoses into one MS-DRG principal-diagnosis exclusion process — a CC/MCC on this list never raises severity when the principal diagnosis is also on it.

O29.91 — Unspecified complication of anesthesia during pregnancy, first trimester, O29.92 — Unspecified complication of anesthesia during pregnancy, second trimester, O29.93 — Unspecified complication of anesthesia during pregnancy, third trimester, O35.7XX0 — Maternal care for (suspected) damage to fetus by other medical procedures, not applicable or unspecified, O35.7XX1 — Maternal care for (suspected) damage to fetus by other medical procedures, fetus 1, O35.7XX2 — Maternal care for (suspected) damage to fetus by other medical procedures, fetus 2, O35.7XX3 — Maternal care for (suspected) damage to fetus by other medical procedures, fetus 3, O35.7XX4 — Maternal care for (suspected) damage to fetus by other medical procedures, fetus 4, O35.7XX5 — Maternal care for (suspected) damage to fetus by other medical procedures, fetus 5, O35.7XX9 — Maternal care for (suspected) damage to fetus by other medical procedures, other fetus, O75.4 — Other complications of obstetric surgery and procedures, O75.81 — Maternal exhaustion complicating labor and delivery, O75.89 — Other specified complications of labor and delivery, O75.9 — Complication of labor and delivery, unspecified, O80 — Encounter for full-term uncomplicated delivery, O90.89 — Other complications of the puerperium, not elsewhere classified, O99.111 — Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, first trimester, O99.112 — Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, second trimester, O99.113 — Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, third trimester, O99.119 — Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, unspecified trimester, +200 more

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Complications specified during childbirth).

O74.3 — Central nervous system complications of anesthesia during labor and delivery, O74.4 — Toxic reaction to local anesthesia during labor and delivery, O74.5 — Spinal and epidural anesthesia-induced headache during labor and delivery, O74.6 — Other complications of spinal and epidural anesthesia during labor and delivery, O74.7 — Failed or difficult intubation for anesthesia during labor and delivery, O74.8 — Other complications of anesthesia during labor and delivery, O74.9 — Complication of anesthesia during labor and delivery, unspecified, O75.0 — Maternal distress during labor and delivery, O75.1 — Shock during or following labor and delivery, O75.2 — Pyrexia during labor, not elsewhere classified, O75.4 — Other complications of obstetric surgery and procedures, O75.5 — Delayed delivery after artificial rupture of membranes, O75.81 — Maternal exhaustion complicating labor and delivery, O75.82 — Onset (spontaneous) of labor after 37 completed weeks of gestation but before 39 completed weeks gestation, with delivery by (planned) cesarean section, O75.89 — Other specified complications of labor and delivery, O75.9 — Complication of labor and delivery, unspecified, O76 — Abnormality in fetal heart rate and rhythm complicating labor and delivery, O77.0 — Labor and delivery complicated by meconium in amniotic fluid, O82 — Encounter for cesarean delivery without indication, O86.0 — Infection of obstetric surgical wound, +91 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main term “Sepsis”; these codes share that main term but sit in a different category of the Tabular List.

A41.89 — Other specified sepsis (specified organism NEC), A41.9 — Sepsis, unspecified organism, A42.7 — Actinomycotic sepsis (actinomycotic), A54.86 — Gonococcal sepsis (gonococcal), B00.7 — Disseminated herpesviral disease (herpesviral), B37.7 — Candidal sepsis (candidal), J95.02 — Infection of tracheostomy stoma (tracheostomy stoma), K65.1 — Peritoneal abscess (intra-abdominal), O08.0 — Genital tract and pelvic infection following ectopic and molar pregnancy (following, abortion), O08.82 — Sepsis following ectopic and molar pregnancy (with, ectopic or molar pregnancy), O85 — Puerperal sepsis (puerperal, postpartum, childbirth), O86.04 — Sepsis following an obstetrical procedure (following, obstetrical procedure), P36.0 — Sepsis of newborn due to streptococcus, group B (newborn, due to, Streptococcus, group B), P36.10 — Sepsis of newborn due to unspecified streptococci (newborn, due to, Streptococcus), P36.19 — Sepsis of newborn due to other streptococci (newborn, due to, Streptococcus, specified NEC), P36.2 — Sepsis of newborn due to Staphylococcus aureus (newborn, due to, Staphylococcus, aureus), P36.30 — Sepsis of newborn due to unspecified staphylococci (newborn, due to, Staphylococcus), P36.39 — Sepsis of newborn due to other staphylococci (newborn, due to, Staphylococcus, specified NEC), P36.4 — Sepsis of newborn due to Escherichia coli (newborn, due to, Escherichia coli), P36.5 — Sepsis of newborn due to anaerobes (newborn, due to, anaerobes NEC), +58 more

Contextual Map

Every relationship of O75.3 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run O75.3 with these 21 related codes in Claim Check

Hierarchy

Use Additional Code

Referenced by Excludes1 notes (9)

Referenced by Excludes2 notes (12)

Referenced by Code First instructions

  • A40 — Streptococcal sepsis[Code First]: “streptococcal sepsis during labor (O75.3)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
  • A41 — Other sepsis[Code First]: “sepsis during labor (O75.3)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Clinical classification (CCSR)

MS-DRG Grouper

MDC crossing

  • MDC 14 — Pregnancy, Childbirth and the Puerperium[MDC crossing]: “Pregnancy, Childbirth and the Puerperium — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 94 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026

Index entries

  • Infection, infected, infective (opportunistic), during labor NEC[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
  • Sepsis (generalized) (unspecified organism), during labor[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026

Nearest codes (11)

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder structured relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "O75.3 — Other infection during labor." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/o75.3-other-infection-during-labor

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Other infection during labor

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to O75.3 in its code family, with their registry titles.

View all codes in the O75 family