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P50.4 ICD-10-CM Code: Newborn affected by hemorrhage into maternal circulation

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Tabular directives
6 Excludes1

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v44, Appendix B.

  • MS-DRG 791 — PREMATURITY WITH MAJOR PROBLEMS (MDC 15)
  • MS-DRG 793 — FULL TERM NEONATE WITH MAJOR PROBLEMS (MDC 15)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for P50.4 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2027Effective: October 1, 2026

Trace:FY2027 changesChange historyRelease, file and checksum

Notes without a marker are published on P50.4 itself; “inherited from” names the category or block whose note applies here.

Excludes1 — Not Coded Here

Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Coder workflow for P50.4

MedCoder structured workflow — derived from this code’s own official record

Before you code P50.4

  1. Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with P50.4. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).

    See the official tabular notes

Choose the right path

  1. Does the documentation support a condition named in P50.4’s Excludes1 note?
    Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
    No → Continue.

    ReviewP61.3, Q44.3, E80.5, E80.6, E80.4

Consider P50.4. Then confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).

Official instructions as workflow

  • Excludes1 — check before selecting P50.4(6 notes)

    Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with P50.4: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.

    CompareP61.3, Q44.3, E80.5, E80.6, E80.4

    See the official tabular notes · Guidelines I.A.12.a

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Documentation: Both the condition P50.4 describes and a condition named in its Excludes1 note are documented for the same encounter.

Coding question: Can both codes be reported?

Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.

Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).

ReviewP61.3, Q44.3, E80.5, E80.6, E80.4

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Don’t confuse P50.4 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of P50.4 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

  • P61.3— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of congenital anemia from intrauterine (fetal) blood loss moves the case to P61.3; the two are not reported together unless documented as unrelated.

    Full comparison: P50.4 vs P61.3 →

  • Q44.3— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of congenital stenosis and stricture of bile ducts moves the case to Q44.3; the two are not reported together unless documented as unrelated.

    Full comparison: P50.4 vs Q44.3 →

  • E80.5— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of Crigler-Najjar syndrome moves the case to E80.5; the two are not reported together unless documented as unrelated.

    Full comparison: P50.4 vs E80.5 →

  • E80.6— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of Dubin-Johnson syndrome moves the case to E80.6; the two are not reported together unless documented as unrelated.

    Full comparison: P50.4 vs E80.6 →

  • E80.4— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of Gilbert syndrome moves the case to E80.4; the two are not reported together unless documented as unrelated.

    Full comparison: P50.4 vs E80.4 →

  • D55— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of hereditary hemolytic anemias moves the case to D55; the two are not reported together unless documented as unrelated.

    Full comparison: P50.4 vs D55 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Code Overview

Newborn affected by hemorrhage into maternal circulation is a billable ICD-10-CM diagnosis code (P50.4).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Indexed Clinical Terms (1)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Verify Before Coding

  • No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name P50.4 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 1 Excludes1 note: P54 — Other neonatal hemorrhages (via P50.-).

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 10 Excludes2 notes: R70 — Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity (via P50.-), R70-R79 — Abnormal findings on examination of blood, without diagnosis (R70-R79) (via P50.-), R71 — Abnormality of red blood cells (via P50.-), R73 — Elevated blood glucose level (via P50.-), R74 — Abnormal serum enzyme levels (via P50.-), R75 — Inconclusive laboratory evidence of human immunodeficiency virus [HIV] (via P50.-), R76 — Other abnormal immunological findings in serum (via P50.-), R77 — Other abnormalities of plasma proteins (via P50.-), R78 — Findings of drugs and other substances, not normally found in blood (via P50.-), R79 — Other abnormal findings of blood chemistry (via P50.-).

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

MS-DRG Grouper Relationships (FY2027)

Potential MS-DRG participation — not a DRG assignment.

FY2027 MS-DRG: not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity for that release.

Named in the grouper logic of 2 MS-DRGs: DRG 791 (MDC 15), DRG 793 (MDC 15).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):PNL011 — Hemorrhagic and hematologic disorders of newborn (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Hemorrhagic and hematologic disorders of newborn).

P50.0 — Newborn affected by intrauterine (fetal) blood loss from vasa previa, P50.1 — Newborn affected by intrauterine (fetal) blood loss from ruptured cord, P50.2 — Newborn affected by intrauterine (fetal) blood loss from placenta, P50.3 — Newborn affected by hemorrhage into co-twin, P50.5 — Newborn affected by intrauterine (fetal) blood loss from cut end of co-twin's cord, P50.8 — Newborn affected by other intrauterine (fetal) blood loss, P50.9 — Newborn affected by intrauterine (fetal) blood loss, unspecified, P51.0 — Massive umbilical hemorrhage of newborn, P51.8 — Other umbilical hemorrhages of newborn, P51.9 — Umbilical hemorrhage of newborn, unspecified, P52.0 — Intraventricular (nontraumatic) hemorrhage, grade 1, of newborn, P52.1 — Intraventricular (nontraumatic) hemorrhage, grade 2, of newborn, P52.21 — Intraventricular (nontraumatic) hemorrhage, grade 3, of newborn, P52.22 — Intraventricular (nontraumatic) hemorrhage, grade 4, of newborn, P52.3 — Unspecified intraventricular (nontraumatic) hemorrhage of newborn, P52.4 — Intracerebral (nontraumatic) hemorrhage of newborn, P52.5 — Subarachnoid (nontraumatic) hemorrhage of newborn, P52.6 — Cerebellar (nontraumatic) and posterior fossa hemorrhage of newborn, P52.8 — Other intracranial (nontraumatic) hemorrhages of newborn, P52.9 — Intracranial (nontraumatic) hemorrhage of newborn, unspecified, +20 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main term “Newborn”; these codes share that main term but sit in a different category of the Tabular List.

P36.5 — Sepsis of newborn due to anaerobes (sepsis, due to, anaerobes NEC), P36.8 — Other bacterial sepsis of newborn (sepsis, specified NEC), P36.9 — Bacterial sepsis of newborn, unspecified (sepsis), P37.5 — Neonatal candidiasis (infection, candidal), P38.1 — Omphalitis with mild hemorrhage (omphalitis, with mild hemorrhage), P38.9 — Omphalitis without hemorrhage (omphalitis), P39.0 — Neonatal infective mastitis (mastitis), P39.3 — Neonatal urinary tract infection (infection, urinary tract), P39.8 — Other specified infections specific to the perinatal period (infection, specified NEC), P39.9 — Infection specific to the perinatal period, unspecified (infection), P52.0 — Intraventricular (nontraumatic) hemorrhage, grade 1, of newborn (affected by, hemorrhage, subependymal), P52.1 — Intraventricular (nontraumatic) hemorrhage, grade 2, of newborn (affected by, bleeding, ventricles), P52.21 — Intraventricular (nontraumatic) hemorrhage, grade 3, of newborn (affected by, hemorrhage, intraventricular, grade 3), P52.22 — Intraventricular (nontraumatic) hemorrhage, grade 4, of newborn (affected by, bleeding, cerebral cortex), P52.3 — Unspecified intraventricular (nontraumatic) hemorrhage of newborn (affected by, hemorrhage, intraventricular), P52.4 — Intracerebral (nontraumatic) hemorrhage of newborn (affected by, hemorrhage, intracerebral), P52.5 — Subarachnoid (nontraumatic) hemorrhage of newborn (affected by, hemorrhage, subarachnoid), P52.6 — Cerebellar (nontraumatic) and posterior fossa hemorrhage of newborn (affected by, hemorrhage, cerebellar), P52.8 — Other intracranial (nontraumatic) hemorrhages of newborn (affected by, hemorrhage, intracranial, specified NEC), P52.9 — Intracranial (nontraumatic) hemorrhage of newborn, unspecified (affected by, hemorrhage, intracranial), +141 more

Lab tests where this diagnosis supports Medicare coverage (NCD)

Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.

Partial Thromboplastin Time (PTT) Test, Prothrombin Time Test and INR (PT/INR)

Contextual Map

Every relationship of P50.4 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run P50.4 with these 9 related codes in Claim Check

Hierarchy

Referenced by Excludes1 notes

  • P54 — Other neonatal hemorrhages[Excludes1](via P50.-): “newborn affected by (intrauterine) blood loss (P50.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Referenced by Excludes2 notes (10)

Clinical classification (CCSR)

MS-DRG Grouper

MDC crossing

Index entries

  • Newborn (infant) (liveborn) (singleton), affected by, intrauterineblood loss (fetal), due to (from), hemorrhage into, maternal circulation[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026

Nearest codes

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2027 tabular list, index and tables, effective October 1, 2026 Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v44.0 (October 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v44 Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder structured relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "P50.4 — Newborn affected by hemorrhage into maternal circulation." ICD-10-CM FY2027. https://medcoder.ai/icd10/code/p50.4-newborn-affected-by-hemorrhage-into-maternal-circulation

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Newborn affected by hemorrhage into maternal circulation

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027, and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to P50.4 in its code family, with their registry titles.

View all codes in the P50 family