QA0.0131 ICD-10-CM Code: SLC6A1-related disorder

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for QA0.0131 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025

Notes without a marker are published on QA0.0131 itself; “inherited from” names the category or block whose note applies here.

7th Character Guide

Variant codes in this family

QA0.0131, QA0.0139

Character meanings are CMS's official 7th-character extensions for this family, as carried in each variant code's official description; variant codes are registry rows. The explanation of how the encounter character is assigned is MedCoder editorial, distinct from the official content above it.

Coder workflow for QA0.0131

MedCoder structured workflow — derived from this code’s own official record

Before you code QA0.0131

1. A 7th character is required in this family. Confirm the documentation supports the character assigned — its meaning in this family is defined in the official instruction. This page’s code carries “1”. The official 7th-character definitions for this family are quoted in the guide.

   See the 7th Character Guide

Choose the right path

1. Does the documentation support one of this family’s 7th-character values?
   Yes → Assign the matching 7th character; the variant codes are in the 7th Character Guide.
   No → The code is invalid without its 7th character — query for the missing element.

Consider QA0.0131. Then review the Code Also note, and confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement

Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).

7th-character basis

The documented element this family’s 7th character records (see the official definitions in the 7th Character Guide).

Official instructions as workflow

• Code Also — related condition(7 notes)

  Coding workflow: Review the related condition when both are documented and the instruction applies. A Code Also note does not fix sequencing; the order follows the circumstances of the encounter.

  ReviewF90, F84.0, G93.45, G40, F84

  See the official tabular notes · Guidelines I.A.17

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Indexed Clinical Terms (2)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

• Deficiency, deficient, GABA transporter 1
• Disorder (of), neurodevelopmental, SLC6A1-related

Don’t confuse QA0.0131 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of QA0.0131 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

• QA0.0139— Encounter relationship (Review)

  Same underlying diagnosis, different encounter phase.

  The same diagnosis at a different phase of care; one encounter takes one 7th character.

  What moves you there: Documentation of a related to pathogenic variant in other transporter or solute carrier gene moves the case to QA0.0139.

  Full comparison: QA0.0131 vs QA0.0139 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Verify Before Coding

• CC as a secondary diagnosis (FY2026). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

FY2026 MS-DRG: CC — Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 39 clinically related codes on its CMS exclusion list.

Named in the grouper logic of 3 MS-DRGs: DRG 564 (MDC 08), DRG 565 (MDC 08), DRG 566 (MDC 08).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Related Codes

Same clinical process (MS-DRG)

Acts as CC — raises the severity of other admissions. CMS groups these diagnoses into one MS-DRG principal-diagnosis exclusion process — a CC/MCC on this list never raises severity when the principal diagnosis is also on it.

Q89.81 — Kabuki syndrome, Q89.89 — Other specified congenital malformations, Q99.2 — Fragile X chromosome, Q99.811 — Usher syndrome, type 1, Q99.812 — Usher syndrome, type 2, Q99.813 — Usher syndrome, type 3, Q99.818 — Other Usher syndrome, Q99.819 — Usher syndrome, unspecified, QA0.0101 — SCN2A-related neurodevelopmental disorder, QA0.0102 — CACNA1A-related neurodevelopmental disorder, QA0.0109 — Neurodevelopmental disorder related to pathogenic variant in other ion channel gene, QA0.011 — Neurodevelopmental disorders, related to pathogenic variants in glutamate receptor genes, QA0.012 — Neurodevelopmental disorders, related to pathogenic variants in other receptor genes, QA0.0139 — Neurodevelopmental disorder, related to pathogenic variant in other transporter or solute carrier gene, QA0.0141 — Syntaxin-binding protein 1-related disorder, QA0.0142 — DLG4-related synaptopathy, QA0.0149 — Neurodevelopmental disorder, related to pathogenic variant in other synapse related gene, QA0.0151 — FOXG1 syndrome, QA0.0159 — Neurodevelopmental disorder, related to other genes associated with transcription and gene expression, QA0.8 — Other neurodevelopmental disorders related to pathogenic variants in other specific genes, +18 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main term “Deficiency, deficient”; these codes share that main term but sit in a different category of the Tabular List.

K06.8 — Other specified disorders of gingiva and edentulous alveolar ridge (vertical ridge), K11.7 — Disturbances of salivary secretion (secretion, salivary gland), K86.89 — Other specified diseases of pancreas (lipocaic), M04.1 — Periodic fever syndromes (mevalonate kinase), M04.8 — Other autoinflammatory syndromes (of interleukin 1 receptor antagonist [DIRA]), M83.8 — Other adult osteomalacia (ergosterol, with, adult osteomalacia), N36.42 — Intrinsic sphincter deficiency (ISD) (sphincter, intrinsic), N36.43 — Combined hypermobility of urethra and intrinsic sphincter deficiency (intrinsic, sphincter, with urethral hypermobility), N47.3 — Deficient foreskin (prepuce), N81.89 — Other female genital prolapse (perineum), O08.1 — Delayed or excessive hemorrhage following ectopic and molar pregnancy (coagulation NOS, with, molar pregnancy), O72.3 — Postpartum coagulation defects (coagulation NOS, postpartum), P53 — Hemorrhagic disease of newborn (menadione, newborn), P61.6 — Other transient neonatal disorders of coagulation (coagulation NOS, newborn, transient), Q10.6 — Other congenital malformations of lacrimal apparatus (lacrimal fluid, congenital), Q75.009 — Craniosynostosis, unspecified (craniofacial axis), Q78.8 — Other specified osteochondrodysplasias (short stature homeobox gene, with, dyschondrosteosis), Q79.4 — Prune belly syndrome (abdominal muscle syndrome), Q96.9 — Turner's syndrome, unspecified (short stature homeobox gene, with, Turner's syndrome), R34 — Anuria and oliguria (secretion, urine), +174 more

Contextual Map

Every relationship of QA0.0131 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Hierarchy

• Q00-QA1 — Chapter 17: Congenital Malformations, Deformations and Chromosomal Abnormalities (Q00-QA1) (Q00-QA1)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026

MS-DRG Grouper

• CC — Complication or Comorbidity [MS-DRG severity]: “As a secondary diagnosis this code can raise the stay's MS-DRG severity tier (CC).”— CMS MS-DRG Definitions Manual (Appendix C) · FY2026
• DRG 564 — OTHER MUSCULOSKELETAL SYSTEM AND CONNECTIVE TISSUE DIAGNOSES WITH MCC[MS-DRG]: “OTHER MUSCULOSKELETAL SYSTEM AND CONNECTIVE TISSUE DIAGNOSES WITH MCC (MDC 08)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
• DRG 565 — OTHER MUSCULOSKELETAL SYSTEM AND CONNECTIVE TISSUE DIAGNOSES WITH CC[MS-DRG]: “OTHER MUSCULOSKELETAL SYSTEM AND CONNECTIVE TISSUE DIAGNOSES WITH CC (MDC 08)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
• DRG 566 — OTHER MUSCULOSKELETAL SYSTEM AND CONNECTIVE TISSUE DIAGNOSES WITHOUT CC/MCC[MS-DRG]: “OTHER MUSCULOSKELETAL SYSTEM AND CONNECTIVE TISSUE DIAGNOSES WITHOUT CC/MCC (MDC 08)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026

MDC crossing

• MDC 08 — Diseases and Disorders of the Musculoskeletal System and Connective Tissue[MDC crossing]: “Diseases and Disorders of the Musculoskeletal System and Connective Tissue — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 18,508 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026

Index entries

• Deficiency, deficient, GABA transporter 1[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
• Disorder (of), neurodevelopmental, SLC6A1-related[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026

Nearest codes (19)

• QA0 — Neurodevelopmental disorders related to specific genetic pathogenic variants[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• QA0.0 — Neurodevelopmental disorders related to pathogenic variants in specific genes[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• QA0.01 — Neurodevelopmental disorders related to pathogenic variants in certain specific genes[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• QA0.010 — Neurodevelopmental disorders, related to pathogenic variants in ion channel genes[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• QA0.0101 — SCN2A-related neurodevelopmental disorder[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• QA0.0102 — CACNA1A-related neurodevelopmental disorder[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• QA0.0109 — Neurodevelopmental disorder related to pathogenic variant in other ion channel gene[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• QA0.011 — Neurodevelopmental disorders, related to pathogenic variants in glutamate receptor genes[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• and 11 more

Change history

• FY2026 — Added to the code set[Change history]— CMS release files (code change ledger) · icd10cm-fy2026

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data

CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page

Claim edits Official source data

CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page

Inpatient payment groups Official source data

CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page

Change history and date-of-service validity Official source data

CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page

Comparisons, relationships and the contextual map MedCoder structured relationship

Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears

Summary and FAQ answers MedCoder explanation

Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Nearest Codes in This Family

Official ICD-10-CM classifications closest to QA0.0131 in its code family, with their registry titles.

• QA0.0102 — CACNA1A-related neurodevelopmental disorder
• QA0.0109 — Neurodevelopmental disorder related to pathogenic variant in other ion channel gene
• QA0.011 — Neurodevelopmental disorders, related to pathogenic variants in glutamate receptor genes
• QA0.012 — Neurodevelopmental disorders, related to pathogenic variants in other receptor genes
• QA0.013 — Neurodevelopmental disorders, related to pathogenic variants in other transporter and solute carrier genes
• QA0.0139 — Neurodevelopmental disorder, related to pathogenic variant in other transporter or solute carrier gene
• QA0.014 — Neurodevelopmental disorders, related to pathogenic variants in synapse related genes
• QA0.0141 — Syntaxin-binding protein 1-related disorder
• QA0.0142 — DLG4-related synaptopathy
• QA0.0149 — Neurodevelopmental disorder, related to pathogenic variant in other synapse related gene

View all codes in the QA0 family