S38.221A ICD-10-CM Code: Complete traumatic amputation of penis, initial encounter

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for S38.221A in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2027Effective: October 1, 2026

Trace:FY2027 changesChange historyRelease, file and checksum

Notes without a marker are published on S38.221A itself; “inherited from” names the category or block whose note applies here.

7th Character Guide

"The appropriate 7th character is to be added to each code from category S38"

• A — initial encounter (this page’s code)
• D — subsequent encounter
• S — sequela

How the encounter character is assigned. “Initial encounter” means the patient is receiving active treatment for the condition — it is not limited to the first visit, and a different or new provider giving active treatment still assigns it. “Subsequent encounter” covers care during the healing or recovery phase after active treatment. “Sequela” is for complications or conditions that arise as a direct result of the original condition.

ICD-10-CM Official Guidelines for Coding and Reporting, Section I.C.19.a (paraphrased by MedCoder).

Variant codes in this family

S38.221A, S38.221D, S38.221S

Character meanings are CMS's official 7th-character extensions for this family, as carried in each variant code's official description; variant codes are registry rows. The explanation of how the encounter character is assigned is MedCoder editorial, distinct from the official content above it.

Don’t confuse S38.221A with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of S38.221A — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

• S38.221D— Encounter relationship (Review)

  Same underlying diagnosis, different encounter phase.

  The same diagnosis at a different phase of care; one encounter takes one 7th character.

  What moves you there: Documentation of a subsequent encounter moves the case to S38.221D.

  Full comparison: S38.221A vs S38.221D →

• S38.221S— Encounter relationship (Review)

  Same underlying diagnosis, different encounter phase.

  The same diagnosis at a different phase of care; one encounter takes one 7th character.

  What moves you there: Documentation of a sequela moves the case to S38.221S.

  Full comparison: S38.221A vs S38.221S →

• T20— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of burns and corrosions adds T20; it is not part of this code and both may be reported when both are documented.

  Full comparison: S38.221A vs T20 →

• T32— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of burns and corrosions adds T32; it is not part of this code and both may be reported when both are documented.

  Full comparison: S38.221A vs T32 →

• T18.5— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of effects of foreign body in anus and rectum adds T18.5; it is not part of this code and both may be reported when both are documented.

  Full comparison: S38.221A vs T18.5 →

• T19— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of effects of foreign body in genitourinary tract adds T19; it is not part of this code and both may be reported when both are documented.

  Full comparison: S38.221A vs T19 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Verify Before Coding

• No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder-derived relationships — computed from published CMS and AHRQ datasets

Other codes that name S38.221A or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 1 Excludes1 note: S31 — Open wound of abdomen, lower back, pelvis and external genitals (via S38.2.-).

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

MS-DRG Grouper Relationships (FY2027)

Potential MS-DRG participation — not a DRG assignment.

FY2027 MS-DRG: not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity for that release.

Named in the grouper logic of 5 MS-DRGs: DRG 729 (MDC 12), DRG 730 (MDC 12), DRG 963 (MDC 24), DRG 964 (MDC 24), DRG 965 (MDC 24).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):INJ015 — Amputation of other body parts, initial encounter (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same injury, other encounter phase

Same injury, coded at a different phase of treatment via the 7th character.

S38.221D — Complete traumatic amputation of penis, subsequent encounterCompare S38.221A vs S38.221D →, S38.221S — Complete traumatic amputation of penis, sequelaCompare S38.221A vs S38.221S →

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Amputation of other body parts, initial encounter).

S08.119A — Complete traumatic amputation of unspecified ear, initial encounter, S08.121A — Partial traumatic amputation of right ear, initial encounter, S08.122A — Partial traumatic amputation of left ear, initial encounter, S08.129A — Partial traumatic amputation of unspecified ear, initial encounter, S08.811A — Complete traumatic amputation of nose, initial encounter, S08.812A — Partial traumatic amputation of nose, initial encounter, S08.89XA — Traumatic amputation of other parts of head, initial encounter, S28.1XXA — Traumatic amputation (partial) of part of thorax, except breast, initial encounter, S28.211A — Complete traumatic amputation of right breast, initial encounter, S28.212A — Complete traumatic amputation of left breast, initial encounter, S28.219A — Complete traumatic amputation of unspecified breast, initial encounter, S28.221A — Partial traumatic amputation of right breast, initial encounter, S28.222A — Partial traumatic amputation of left breast, initial encounter, S28.229A — Partial traumatic amputation of unspecified breast, initial encounter, S38.211A — Complete traumatic amputation of female external genital organs, initial encounter, S38.212A — Partial traumatic amputation of female external genital organs, initial encounter, S38.222A — Partial traumatic amputation of penis, initial encounter, S38.231A — Complete traumatic amputation of scrotum and testis, initial encounter, S38.232A — Partial traumatic amputation of scrotum and testis, initial encounter, S38.3XXA — Transection (partial) of abdomen, initial encounter, +2 more

Contextual Map

Every relationship of S38.221A in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run S38.221A with this related code in Claim Check

Hierarchy

• S00-T88 — Chapter 19: Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) (S00-T88)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
• S30-S39 — Injuries to the abdomen, lower back, lumbar spine, pelvis and external genitals[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2027

Referenced by Excludes1 notes

• S31 — Open wound of abdomen, lower back, pelvis and external genitals[Excludes1](via S38.2.-): “traumatic amputation of part of abdomen, lower back and pelvis (S38.2-, S38.3)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2027

Clinical classification (CCSR)

• INJ015 — Amputation of other body parts, initial encounter[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)

MS-DRG Grouper

• DRG 729 — OTHER MALE REPRODUCTIVE SYSTEM DIAGNOSES WITH CC/MCC[MS-DRG]: “OTHER MALE REPRODUCTIVE SYSTEM DIAGNOSES WITH CC/MCC (MDC 12)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
• DRG 730 — OTHER MALE REPRODUCTIVE SYSTEM DIAGNOSES WITHOUT CC/MCC[MS-DRG]: “OTHER MALE REPRODUCTIVE SYSTEM DIAGNOSES WITHOUT CC/MCC (MDC 12)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
• DRG 963 — OTHER MULTIPLE SIGNIFICANT TRAUMA WITH MCC[MS-DRG]: “OTHER MULTIPLE SIGNIFICANT TRAUMA WITH MCC (MDC 24)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
• DRG 964 — OTHER MULTIPLE SIGNIFICANT TRAUMA WITH CC[MS-DRG]: “OTHER MULTIPLE SIGNIFICANT TRAUMA WITH CC (MDC 24)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
• DRG 965 — OTHER MULTIPLE SIGNIFICANT TRAUMA WITHOUT CC/MCC[MS-DRG]: “OTHER MULTIPLE SIGNIFICANT TRAUMA WITHOUT CC/MCC (MDC 24)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2027

MDC crossing

• MDC 12 — Diseases and Disorders of the Male Reproductive System[MDC crossing]: “Diseases and Disorders of the Male Reproductive System — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 1,969 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2027
• MDC 24 — Multiple Significant Trauma[MDC crossing]: “Multiple Significant Trauma — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 22,991 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2027

Index entries

• Amputation, traumatic (complete) (partial), genital organ (s) (external), male, penis (complete)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
• Amputation, traumatic (complete) (partial), penis (complete)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027

Nearest codes (40)

• S38 — Crushing injury and traumatic amputation of abdomen, lower back, pelvis and external genitals[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
• S38.02XS — Crushing injury of scrotum and testis, sequela[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
• S38.03 — Crushing injury of vulva[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
• S38.03XA — Crushing injury of vulva, initial encounter[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
• S38.03XD — Crushing injury of vulva, subsequent encounter[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
• S38.03XS — Crushing injury of vulva, sequela[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
• S38.1 — Crushing injury of abdomen, lower back, and pelvis[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
• S38.1XXA — Crushing injury of abdomen, lower back, and pelvis, initial encounter[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2027
• and 32 more

Change history

• FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Indexed Clinical Terms (2)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

• Amputation, traumatic (complete) (partial), genital organ (s) (external), male, penis (complete)
• Amputation, traumatic (complete) (partial), penis (complete)

Common coding questions

MedCoder editorial

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data

CMS/CDC ICD-10-CM FY2027 tabular list, index and tables, effective October 1, 2026 Release, file and checksum · Publisher’s page

Claim edits Official source data

CMS Definitions of Medicare Code Edits — v44.0 (October 2026) Release, file and checksum · Publisher’s page

Inpatient payment groups Official source data

CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v44 Release, file and checksum · Publisher’s page

Change history and date-of-service validity Official source data

CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page

Comparisons, relationships and the contextual map MedCoder-derived relationship

Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears

Summary and FAQ answers MedCoder editorial explanation

Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 20, 2026 · All releases and sources

Labels on this page: Official source data · MedCoder-derived relationship · MedCoder editorial explanation. How to read the labels · All data sources and release dates · CMS coding rules

Nearest Codes in This Family

Official ICD-10-CM classifications closest to S38.221A in its code family, with their registry titles.

• S38.212A — Partial traumatic amputation of female external genital organs, initial encounter
• S38.212D — Partial traumatic amputation of female external genital organs, subsequent encounter
• S38.212S — Partial traumatic amputation of female external genital organs, sequela
• S38.22 — Traumatic amputation of penis
• S38.221 — Complete traumatic amputation of penis
• S38.221D — Complete traumatic amputation of penis, subsequent encounter
• S38.221S — Complete traumatic amputation of penis, sequela
• S38.222 — Partial traumatic amputation of penis
• S38.222A — Partial traumatic amputation of penis, initial encounter
• S38.222D — Partial traumatic amputation of penis, subsequent encounter

View all codes in the S38 family