T49.5X2D ICD-10-CM Code: Poisoning by ophthalmological drugs and preparations, intentional self-harm, subsequent encounter

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for T49.5X2D in the official ICD-10-CM tabular list, quoted as published.

Notes without a marker are published on T49.5X2D itself; “inherited from” names the category or block whose note applies here.

7th Character Guide

"The appropriate 7th character is to be added to each code from category T49"

• A — initial encounter
• D — subsequent encounter (this page’s code)
• S — sequela

How the encounter character is assigned. “Initial encounter” means the patient is receiving active treatment for the condition — it is not limited to the first visit, and a different or new provider giving active treatment still assigns it. “Subsequent encounter” covers care during the healing or recovery phase after active treatment. “Sequela” is for complications or conditions that arise as a direct result of the original condition.

ICD-10-CM Official Guidelines for Coding and Reporting, Section I.C.19.a (paraphrased by MedCoder).

Variant codes in this family

T49.5X2A, T49.5X2D, T49.5X2S

Character meanings are CMS's official 7th-character extensions for this family, as carried in each variant code's official description; variant codes are registry rows. The explanation of how the encounter character is assigned is MedCoder editorial, distinct from the official content above it.

Coder workflow for T49.5X2D

MedCoder structured workflow — derived from this code’s own official record

Before you code T49.5X2D

1. A 7th character is required in this family. Confirm the documented encounter: initial (active treatment), subsequent (healing or recovery phase), or sequela. This page’s code carries “D”. “Initial” means active treatment, not the first visit (Guidelines I.C.19.a).

   See the 7th Character Guide · Guide: 7th characters: initial, subsequent, sequela →

2. Confirm whether the documentation describes a poisoning, an adverse effect of a correctly prescribed and administered drug, an underdosing, or a toxic effect, and the intent where the record states it: the Table of Drugs and Chemicals separates these by column, and the sequencing differs for each. Poisoning, adverse effect and underdosing guidelines (Guidelines I.C.19.e).

   See the Table of Drugs and Chemicals entries · Guide: Poisoning vs adverse effect vs underdosing →

3. Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with T49.5X2D. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).

   See the official tabular notes

Choose the right path

1. Does the documentation support a condition named in T49.5X2D’s Excludes1 note?
   Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
   No → Continue.

   ReviewO29.3

2. Is the underlying (etiologic) condition the Code First note names documented?
   Yes → Sequence the underlying condition first, then T49.5X2D.
   No → Continue; do not add an underlying condition the record does not document.

   ReviewT88.7, K29, L27

3. Is the encounter phase documented — active treatment, healing or recovery, or a sequela?
   Yes → Assign the matching 7th character; the variant codes are in the 7th Character Guide.
   No → The code is invalid without its 7th character — query for the missing element.

Consider T49.5X2D. Then work the Use Additional Code note, and confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement

Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).

Encounter type

Active treatment, healing or recovery phase, or sequela — the basis of the 7th character (Guidelines I.C.19.a).

The underlying (etiologic) condition

Named in the Code First note; sequenced before this code when documented (Guidelines I.A.13).

The conditions the Use Additional Code note names

Reported with this code when documented; a conditional instruction (“if applicable”, “if known”) applies only when the record supports it.

External cause, place and activity

For the external cause codes reported with the injury or poisoning, where documented (Guidelines I.C.20.a).

Official instructions as workflow

• Excludes1 — check before selecting T49.5X2D(1 note)

  Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with T49.5X2D: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.

  CompareO29.3

  See the official tabular notes · Guidelines I.A.12.a

• Excludes2 — not part of T49.5X2D(5 notes)

  Coding workflow: The conditions named in this note are not included in T49.5X2D. When the record documents both, both may be reported; the note is a boundary, not a prohibition.

  CompareF55, D84.821

  See the official tabular notes · Guidelines I.A.12.b

• Code First — sequencing check(7 notes)

  Coding workflow: Check whether the underlying or etiologic condition the note names is documented. When it is, sequence it before T49.5X2D. Do not add an underlying condition the record does not document.

  ReviewT88.7, K29, L27

  See the official tabular notes · Guidelines I.A.13

• Use Additional Code — after identifying T49.5X2D(4 notes)

  Coding workflow: Check whether the documentation supports the additional code(s) the note names, and report them with T49.5X2D when it does. Where the instruction is conditional (“if applicable”, “if known”), it applies only when the record documents the condition.

  ReviewY63.6, Z91.12, Z91.13

  See the official tabular notes · Guidelines I.A.13

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Associated Substances (33)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Substances from the official ICD-10-CM Table of Drugs and Chemicals that map to this code.

• Befunolol
• Bibrocathol
• Chloroptic
• Contact lens solution
• Cycloplegic drug
• Demecarium (bromide)
• Dendrid
• Dipivefrine
• Echothiophate, echothiopate, ecothiopate
• Ecothiopate iodide
• Edoxudine
• Eserine
• Eucatropine
• Eye agents (anti-infective)
• Eye drug NEC
• Fluorphenylalanine
• Herplex
• Hydroxyamphetamine
• Hypromellose
• Lachesine
• Levobunolol
• Lubricant, eye
• Methylparaben (ophthalmic)
• Metipranolol
• Miotic drug
• Mydriatic drug
• Phospholine
• Physostigmine
• Propylparaben (ophthalmic)
• Stoxil
• Tetrahydrozoline
• Tetryzoline
• Visine

Don’t confuse T49.5X2D with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of T49.5X2D — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

• O29.3— Excludes1 conflict (Conflict)

  Not coded here — these two are mutually exclusive.

  Not reported together with this code, except where the two conditions are documented as unrelated.

  What moves you there: Documentation of toxic reaction to local anesthesia in pregnancy moves the case to O29.3; the two are not reported together unless documented as unrelated.

  Full comparison: T49.5X2D vs O29.3 →

• T49.5X2A— Encounter relationship (Review)

  Same underlying diagnosis, different encounter phase.

  The same diagnosis at a different phase of care; one encounter takes one 7th character.

  What moves you there: Documentation of a initial encounter moves the case to T49.5X2A.

  Full comparison: T49.5X2D vs T49.5X2A →

• T49.5X2S— Encounter relationship (Review)

  Same underlying diagnosis, different encounter phase.

  The same diagnosis at a different phase of care; one encounter takes one 7th character.

  What moves you there: Documentation of a sequela moves the case to T49.5X2S.

  Full comparison: T49.5X2D vs T49.5X2S →

• F10— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of abuse and dependence of psychoactive substances adds F10; it is not part of this code and both may be reported when both are documented.

  Full comparison: T49.5X2D vs F10 →

• F19— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of abuse and dependence of psychoactive substances adds F19; it is not part of this code and both may be reported when both are documented.

  Full comparison: T49.5X2D vs F19 →

• F55— Excludes2 relationship (Informational)

  Distinct conditions — both may be reported.

  A distinct condition — both may be reported when both are documented.

  What moves you there: Documentation of abuse of non-dependence-producing substances adds F55; it is not part of this code and both may be reported when both are documented.

  Full comparison: T49.5X2D vs F55 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Decision Points

The directives on this code's own record, as a pre-claim checklist.

1. A 7th character applies in this family. Confirm the documented encounter matches the character assigned. See the official 7th-character definitions and this code’s variants
2. Sequencing: 7 Code First instructions — the underlying condition is sequenced before this code when present. See the Code First notes
3. 4 Use Additional Code instructions — report the named additional code(s) when the documentation supports them. See the Use Additional Code notes
4. 1 Excludes1 entry — codes named there are generally not reported together with this code (Guidelines I.A.12.a). See the Excludes1 notes
5. 5 Excludes2 entries — those conditions are not part of this code and may be reported additionally when documented. See the Excludes2 notes

Checklist rows are derived from this code's own official directives; the wording of each check is MedCoder editorial. The official notes themselves are in the sections each row links to.

Verify Before Coding

• No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name T49.5X2D or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 2 Excludes1 notes: T37 — Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics (via T49.5.-), T38.0 — Poisoning by, adverse effect of and underdosing of glucocorticoids and synthetic analogues (via T49.-).

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 11 Excludes2 notes across 2 chapters: T80 — Complications following infusion, transfusion and therapeutic injection (via T49.-), T80-T88 — Complications of surgical and medical care, not elsewhere classified (T80-T88) (via T49.-), T81 — Complications of procedures, not elsewhere classified (via T49.-), T82 — Complications of cardiac and vascular prosthetic devices, implants and grafts (via T49.-), T83 — Complications of genitourinary prosthetic devices, implants and grafts (via T49.-), T84 — Complications of internal orthopedic prosthetic devices, implants and grafts (via T49.-), T85 — Complications of other internal prosthetic devices, implants and grafts (via T49.-), T86 — Complications of transplanted organs and tissue (via T49.-), T87 — Complications peculiar to reattachment and amputation (via T49.-), T88 — Other complications of surgical and medical care, not elsewhere classified (via T49.-), Y63 — Failure in dosage during surgical and medical care (via T49.-).

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

Referenced by 20 Code First instructions across 13 chapters: D64.2 — Secondary sideroblastic anemia due to drugs and toxins (via T49.-), E03.2 — Hypothyroidism due to medicaments and other exogenous substances (via T49.-), E09 — Drug or chemical induced diabetes mellitus (via T49.-), F02 — Dementia in other diseases classified elsewhere (via T49.-), G92.8 — Other toxic encephalopathy (via T49.-), G92.9 — Unspecified toxic encephalopathy (via T49.-), H35.38 — Toxic maculopathy (via T49.-), H91.0 — Ototoxic hearing loss (via T49.-), I42.7 — Cardiomyopathy due to drug and external agent (via T49.-), K22.1 — Ulcer of esophagus (via T49.-), K71 — Toxic liver disease (via T49.-), L53.0 — Toxic erythema (via T49.-), M34.2 — Systemic sclerosis induced by drug and chemical (via T49.-), N14 — Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions (via T49.-), P58.4 — Neonatal jaundice due to drugs or toxins transmitted from mother or given to newborn (via T49.-), Z91.12 — Patient's intentional underdosing of medication regimen (via T49.-), Z91.13 — Patient's unintentional underdosing of medication regimen (via T49.-), Z91.14 — Patient's other noncompliance with medication regimen (via T49.-), Z91.A2 — Caregiver's intentional underdosing of patient's medication regimen (via T49.-), Z91.A3 — Caregiver's unintentional underdosing of patient's medication regimen (via T49.-).

Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.

Referenced by 99 Use Additional Code instructions across 15 chapters: D46 — Myelodysplastic syndromes (via T49.-), D52.1 — Drug-induced folate deficiency anemia (via T49.-), D59.0 — Drug-induced autoimmune hemolytic anemia (via T49.-), D59.2 — Drug-induced nonautoimmune hemolytic anemia (via T49.-), D59.39 — Other hemolytic-uremic syndrome (via T49.-), D61.1 — Drug-induced aplastic anemia (via T49.-), D64.2 — Secondary sideroblastic anemia due to drugs and toxins (via T49.-), D70.2 — Other drug-induced agranulocytosis (via T49.-), D72.12 — Drug rash with eosinophilia and systemic symptoms syndrome (via T49.-), D84.821 — Immunodeficiency due to drugs (via T49.-), D89.3 — Immune reconstitution syndrome (via T49.-), E03.2 — Hypothyroidism due to medicaments and other exogenous substances (via T49.-), E06.4 — Drug-induced thyroiditis (via T49.-), E09 — Drug or chemical induced diabetes mellitus (via T49.-), E16.0 — Drug-induced hypoglycemia without coma (via T49.-), E22.1 — Hyperprolactinemia (via T49.-), E23.1 — Drug-induced hypopituitarism (via T49.-), E24.2 — Drug-induced Cushing's syndrome (via T49.-), E25.8 — Other adrenogenital disorders (via T49.-), E27.3 — Drug-induced adrenocortical insufficiency (via T49.-), +79 more.

These codes instruct coders to additionally report this code when it applies.

Referenced by 1 Code Also instruction: Z91.1 — Patient's noncompliance with medical treatment and regimen (via T49.-).

These codes suggest coding this condition alongside when both are present.

MS-DRG Grouper Relationships (FY2026)

Potential MS-DRG participation — not a DRG assignment.

Not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity.

Named in the grouper logic of 2 MS-DRGs: DRG 949 (MDC 23), DRG 950 (MDC 23).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):MBD027 — Suicide attempt/intentional self-harm; subsequent encounter (default); INJ059 — Poisoning by drugs, subsequent encounter.

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same injury, other encounter phase

Same injury, coded at a different phase of treatment via the 7th character.

T49.5X2A — Poisoning by ophthalmological drugs and preparations, intentional self-harm, initial encounterCompare T49.5X2D vs T49.5X2A →, T49.5X2S — Poisoning by ophthalmological drugs and preparations, intentional self-harm, sequela

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical categories (Suicide attempt/intentional self-harm; subsequent encounter, Poisoning by drugs, subsequent encounter).

+896 more

Contextual Map

Every relationship of T49.5X2D in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run T49.5X2D with these 24 related codes in Claim Check

Hierarchy

• S00-T88 — Chapter 19: Injury, Poisoning and Certain Other Consequences of External Causes (S00-T88) (S00-T88)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T36-T50 — Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T47-T50 — Hormones & Systemic Agents[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026

Referenced by Excludes1 notes

• T37 — Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics[Excludes1](via T49.5.-): “anti-infectives topically used for eye (T49.5-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• T38.0 — Poisoning by, adverse effect of and underdosing of glucocorticoids and synthetic analogues[Excludes1](via T49.-): “glucocorticoids, topically used (T49.-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Referenced by Excludes2 notes (11)

• T80 — Complications following infusion, transfusion and therapeutic injection[Excludes2](via T49.-): “poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• T80-T88 — Complications of surgical and medical care, not elsewhere classified (T80-T88)[Excludes2](via T49.-): “poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• T81 — Complications of procedures, not elsewhere classified[Excludes2](via T49.-): “poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• T82 — Complications of cardiac and vascular prosthetic devices, implants and grafts[Excludes2](via T49.-): “poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• T83 — Complications of genitourinary prosthetic devices, implants and grafts[Excludes2](via T49.-): “poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• T84 — Complications of internal orthopedic prosthetic devices, implants and grafts[Excludes2](via T49.-): “poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• T85 — Complications of other internal prosthetic devices, implants and grafts[Excludes2](via T49.-): “poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• T86 — Complications of transplanted organs and tissue[Excludes2](via T49.-): “poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• and 3 more

Referenced by Code First instructions (20)

• D64.2 — Secondary sideroblastic anemia due to drugs and toxins[Code First](via T49.-): “poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• E03.2 — Hypothyroidism due to medicaments and other exogenous substances[Code First](via T49.-): “poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• E09 — Drug or chemical induced diabetes mellitus[Code First](via T49.-): “poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• F02 — Dementia in other diseases classified elsewhere[Code First](via T49.-): “intoxications (T36-T65)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• G92.8 — Other toxic encephalopathy[Code First](via T49.-): “poisoning due to drug or toxin, if applicable, (T36-T65 with fifth or sixth character 1-4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• G92.9 — Unspecified toxic encephalopathy[Code First](via T49.-): “poisoning due to drug or toxin, if applicable, (T36-T65 with fifth or sixth character 1-4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• H35.38 — Toxic maculopathy[Code First](via T49.-): “poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• H91.0 — Ototoxic hearing loss[Code First](via T49.-): “poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• and 12 more

Referenced by Use Additional Code instructions (99)

• D46 — Myelodysplastic syndromes[Use Additional Code](via T49.-): “code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• D52.1 — Drug-induced folate deficiency anemia[Use Additional Code](via T49.-): “code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• D59.0 — Drug-induced autoimmune hemolytic anemia[Use Additional Code](via T49.-): “code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• D59.2 — Drug-induced nonautoimmune hemolytic anemia[Use Additional Code](via T49.-): “code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• D59.39 — Other hemolytic-uremic syndrome[Use Additional Code](via T49.-): “code, if applicable, for adverse effect to identify drug (T36-T50 with fifth or sixth character 5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• D61.1 — Drug-induced aplastic anemia[Use Additional Code](via T49.-): “code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• D64.2 — Secondary sideroblastic anemia due to drugs and toxins[Use Additional Code](via T49.-): “code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• D70.2 — Other drug-induced agranulocytosis[Use Additional Code](via T49.-): “code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
• and 91 more

Referenced by Code Also instructions

• Z91.1 — Patient's noncompliance with medical treatment and regimen[Code Also](via T49.-): “, if applicable, to identify underdosing of specific drug (T36-T50 with final character 6)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026

Clinical classification (CCSR)

• MBD027 — Suicide attempt/intentional self-harm; subsequent encounter[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)
• INJ059 — Poisoning by drugs, subsequent encounter[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)

MS-DRG Grouper

• DRG 949 — AFTERCARE WITH CC/MCC[MS-DRG]: “AFTERCARE WITH CC/MCC (MDC 23)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
• DRG 950 — AFTERCARE WITHOUT CC/MCC[MS-DRG]: “AFTERCARE WITHOUT CC/MCC (MDC 23)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026

MDC crossing

• MDC 23 — Factors Influencing Health Status and Other Contacts with Health Services[MDC crossing]: “Factors Influencing Health Status and Other Contacts with Health Services — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 1,235 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2026

Drugs & chemicals (33)

• Befunolol — Befunolol — Poisoning, Intentional self-harm [Drug table]: “Befunolol (Poisoning, Intentional self-harm)”— CMS Table of Drugs and Chemicals · icd10cm-fy2026
• Bibrocathol — Bibrocathol — Poisoning, Intentional self-harm [Drug table]: “Bibrocathol (Poisoning, Intentional self-harm)”— CMS Table of Drugs and Chemicals · icd10cm-fy2026
• Chloroptic — Chloroptic — Poisoning, Intentional self-harm [Drug table]: “Chloroptic (Poisoning, Intentional self-harm)”— CMS Table of Drugs and Chemicals · icd10cm-fy2026
• Contact lens solution — Contact lens solution — Poisoning, Intentional self-harm [Drug table]: “Contact lens solution (Poisoning, Intentional self-harm)”— CMS Table of Drugs and Chemicals · icd10cm-fy2026
• Cycloplegic drug — Cycloplegic drug — Poisoning, Intentional self-harm [Drug table]: “Cycloplegic drug (Poisoning, Intentional self-harm)”— CMS Table of Drugs and Chemicals · icd10cm-fy2026
• Demecarium (bromide) — Demecarium (bromide) — Poisoning, Intentional self-harm [Drug table]: “Demecarium (bromide) (Poisoning, Intentional self-harm)”— CMS Table of Drugs and Chemicals · icd10cm-fy2026
• Dendrid — Dendrid — Poisoning, Intentional self-harm [Drug table]: “Dendrid (Poisoning, Intentional self-harm)”— CMS Table of Drugs and Chemicals · icd10cm-fy2026
• Dipivefrine — Dipivefrine — Poisoning, Intentional self-harm [Drug table]: “Dipivefrine (Poisoning, Intentional self-harm)”— CMS Table of Drugs and Chemicals · icd10cm-fy2026
• and 25 more

Nearest codes (40)

• T49 — Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T49.4X4 — Poisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, undetermined[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T49.4X4A — Poisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, undetermined, initial encounter[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T49.4X4D — Poisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, undetermined, subsequent encounter[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T49.4X4S — Poisoning by keratolytics, keratoplastics, and other hair treatment drugs and preparations, undetermined, sequela[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T49.4X5 — Adverse effect of keratolytics, keratoplastics, and other hair treatment drugs and preparations[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T49.4X5A — Adverse effect of keratolytics, keratoplastics, and other hair treatment drugs and preparations, initial encounter[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• T49.4X5D — Adverse effect of keratolytics, keratoplastics, and other hair treatment drugs and preparations, subsequent encounter[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
• and 32 more

Change history

• FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Common coding questions

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data

CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page

Claim edits Official source data

CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page

Inpatient payment groups Official source data

CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page

Change history and date-of-service validity Official source data

CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page

Comparisons, relationships and the contextual map MedCoder structured relationship

Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears

Summary and FAQ answers MedCoder explanation

Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Nearest Codes in This Family

Official ICD-10-CM classifications closest to T49.5X2D in its code family, with their registry titles.

• T49.5X1A — Poisoning by ophthalmological drugs and preparations, accidental (unintentional), initial encounter
• T49.5X1D — Poisoning by ophthalmological drugs and preparations, accidental (unintentional), subsequent encounter
• T49.5X1S — Poisoning by ophthalmological drugs and preparations, accidental (unintentional), sequela
• T49.5X2 — Poisoning by ophthalmological drugs and preparations, intentional self-harm
• T49.5X2A — Poisoning by ophthalmological drugs and preparations, intentional self-harm, initial encounter
• T49.5X2S — Poisoning by ophthalmological drugs and preparations, intentional self-harm, sequela
• T49.5X3 — Poisoning by ophthalmological drugs and preparations, assault
• T49.5X3A — Poisoning by ophthalmological drugs and preparations, assault, initial encounter
• T49.5X3D — Poisoning by ophthalmological drugs and preparations, assault, subsequent encounter
• T49.5X3S — Poisoning by ophthalmological drugs and preparations, assault, sequela

View all codes in the T49 family