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ICD-10/T86.91

T86.91 ICD-10-CM Code: Unspecified transplanted organ and tissue rejection

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Inpatient Payment Groups (MS-DRG)

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43.0, Appendix B.

  • MS-DRG 919 — COMPLICATIONS OF TREATMENT WITH MCC (MDC 21)
  • MS-DRG 920 — COMPLICATIONS OF TREATMENT WITH CC (MDC 21)
  • MS-DRG 921 — COMPLICATIONS OF TREATMENT WITHOUT CC/MCC (MDC 21)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Official Registry Overview & Definition

Unspecified transplanted organ and tissue rejection is a billable ICD-10-CM diagnosis code (T86.91).

Official Tabular Instructional Notes

Sequencing, inclusion, and exclusion notes published for T86.91 in the official ICD-10-CM tabular list.

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Use Additional Code

Supplementary codes the tabular list directs you to add.

  • Use additional code to identify other transplant complications, such as:
  • graft-versus-host disease (D89.81-)
  • malignancy associated with organ transplant (C80.2)
  • post-transplant lymphoproliferative disorders (PTLD) (D47.Z1)
  • Use additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • Use additional code(s) to identify the specified condition resulting from the complication
  • Use additional code to identify devices involved and details of circumstances (Y62-Y82)

Change history

No changes recorded for this code — unchanged since the FY2016 baseline of the change ledger.

Verify Before Coding

  • Billable — reportable as written.
  • CC as a secondary diagnosis (FY2026). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim.

Contextual Map

Every relationship of T86.91 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Hierarchy

  • T86.9 — Complication of unspecified transplanted organ and tissue [Hierarchy]

Referenced by Excludes1 notes

  • Z98.85 — Transplanted organ removal status [Excludes1](via T86.-): “encounter for removal of transplanted organ -code to complication of transplanted organ (T86.-)”

Referenced by Excludes2 notes

  • D89 — Other disorders involving the immune mechanism, not elsewhere classified [Excludes2](via T86.-): “transplant failure and rejection (T86.-)”
  • T81 — Complications of procedures, not elsewhere classified [Excludes2](via T86.-): “complications of transplanted organs and tissue (T86.-)”
  • T82 — Complications of cardiac and vascular prosthetic devices, implants and grafts [Excludes2](via T86.-): “failure and rejection of transplanted organs and tissue (T86.-)”
  • T83 — Complications of genitourinary prosthetic devices, implants and grafts [Excludes2](via T86.-): “failure and rejection of transplanted organs and tissue (T86.-)”
  • T84 — Complications of internal orthopedic prosthetic devices, implants and grafts [Excludes2](via T86.-): “failure and rejection of transplanted organs and tissues (T86.-)”
  • T85 — Complications of other internal prosthetic devices, implants and grafts [Excludes2](via T86.-): “failure and rejection of transplanted organs and tissue (T86.-)”

Referenced by Code First instructions

  • C80.2 — Malignant neoplasm associated with transplanted organ [Code First](via T86.-): “complication of transplanted organ (T86.-)”
  • D47.Z1 — Post-transplant lymphoproliferative disorder (PTLD) [Code First](via T86.-): “complications of transplanted organs and tissue (T86.-)”
  • D89.81 — Graft-versus-host disease [Code First](via T86.-): “complications of transplanted organs and tissue (T86.-)”
  • D89.83 — Cytokine release syndrome [Code First](via T86.-): “complications of transplanted organs and tissue (T86.-)”

Clinical classification (CCSR)

  • INJ036 — Complication of transplanted organs or tissue, initial encounter [CCSR]

Potential MS-DRG

  • CC — Complication or Comorbidity [MS-DRG severity]: “As a secondary diagnosis this code can raise the stay's MS-DRG severity tier (CC).”
  • DRG 919 — COMPLICATIONS OF TREATMENT WITH MCC [MS-DRG]: “COMPLICATIONS OF TREATMENT WITH MCC (MDC 21)”
  • DRG 920 — COMPLICATIONS OF TREATMENT WITH CC [MS-DRG]: “COMPLICATIONS OF TREATMENT WITH CC (MDC 21)”
  • DRG 921 — COMPLICATIONS OF TREATMENT WITHOUT CC/MCC [MS-DRG]: “COMPLICATIONS OF TREATMENT WITHOUT CC/MCC (MDC 21)”

Index entries

  • Complication (s) (from) (of), transplant, rejection[Index term]
  • Disorder (of), tubulo-interstitial (in), transplant rejection[Index term]
  • Pyelonephritis, in (due to), transplant rejection[Index term]
  • Rejection, transplant[Index term]
  • Rejection, transplant, organ (immune or nonimmune cause)[Index term]

Nearest codes (40)

  • T86 — Complications of transplanted organs and tissue [Sibling]
  • T86.8402 — Corneal transplant rejection, left eye [Sibling]
  • T86.8403 — Corneal transplant rejection, bilateral [Sibling]
  • T86.8409 — Corneal transplant rejection, unspecified eye [Sibling]
  • T86.841 — Corneal transplant failure [Sibling]
  • T86.8411 — Corneal transplant failure, right eye [Sibling]
  • T86.8412 — Corneal transplant failure, left eye [Sibling]
  • T86.8413 — Corneal transplant failure, bilateral [Sibling]
  • and 32 more

Referenced by Other Codes

Clinical classification (AHRQ CCSR):INJ036 — Complication of transplanted organs or tissue, initial encounter (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Potential MS-DRG Relationships (FY2026)

CC — Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 50 clinically related codes on its CMS exclusion list.

Named in the grouper logic of 3 MS-DRGs: DRG 919 (MDC 21), DRG 920 (MDC 21), DRG 921 (MDC 21).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Official ICD-10-CM tabular notes on other codes that name T86.91 or its code family.

1 Excludes1 notes: Z98.85 (via T86.-).

6 Excludes2 notes across 2 chapters: D89 (via T86.-), T81 (via T86.-), T82 (via T86.-), T83 (via T86.-), T84 (via T86.-), T85 (via T86.-).

4 Code First instructions across 2 chapters: C80.2 (via T86.-), D47.Z1 (via T86.-), D89.81 (via T86.-), D89.83 (via T86.-).

Nearest Codes in This Family

Official ICD-10-CM classifications closest to T86.91 in its code family, with their registry titles.

  • T86.89 — Complications of other transplanted tissue
  • T86.890 — Other transplanted tissue rejection
  • T86.891 — Other transplanted tissue failure
  • T86.892 — Other transplanted tissue infection
  • T86.898 — Other complications of other transplanted tissue
  • T86.899 — Unspecified complication of other transplanted tissue
  • T86.9 — Complication of unspecified transplanted organ and tissue
  • T86.90 — Unspecified complication of unspecified transplanted organ and tissue
  • T86.92 — Unspecified transplanted organ and tissue failure
  • T86.93 — Unspecified transplanted organ and tissue infection

View all codes in the T86 family

Indexed Clinical Terms (5)

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code.

  • Complication (s) (from) (of), transplant, rejection
  • Disorder (of), tubulo-interstitial (in), transplant rejection
  • Pyelonephritis, in (due to), transplant rejection
  • Rejection, transplant
  • Rejection, transplant, organ (immune or nonimmune cause)