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Z78.0 ICD-10-CM Code: Asymptomatic menopausal state

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Tabular directives
2 inclusion terms · 4 Excludes2 · 1 code-also instruction

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v44, Appendix B.

  • MS-DRG 951 — OTHER FACTORS INFLUENCING HEALTH STATUS (MDC 23)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for Z78.0 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2027Effective: October 1, 2026

Trace:FY2027 changesChange historyRelease, file and checksum

Notes without a marker are published on Z78.0 itself; “inherited from” names the category or block whose note applies here.

Inclusion Terms

Alternative terms the tabular list files under this code.

  • Menopausal state NOS
  • Postmenopausal status NOS

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Code Also

Additional codes that may be required to fully describe the encounter.

  • any follow-up examination (Z08-Z09)

Source: inherited from Z77-Z99

Coder workflow for Z78.0

MedCoder structured workflow — derived from this code’s own official record

Before you code Z78.0

  1. Confirm the reason for the encounter this Z code records: the circumstance it records. Check whether the code may be reported as first-listed or principal — some Z codes are limited to one position — and do not report a history or status code for a condition documented as current. Z code categories and their reporting positions (Guidelines I.C.21.c, I.C.21.c.15).

    Guide: Z codes as principal or first-listed diagnosis →

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
The reason for the encounter
Whether the code records the encounter’s purpose, a status, or a history — and whether it may be first-listed (Guidelines I.C.21.c).

Official instructions as workflow

  • Excludes2 — not part of Z78.0(4 notes)

    Coding workflow: The conditions named in this note are not included in Z78.0. When the record documents both, both may be reported; the note is a boundary, not a prohibition.

    CompareN95.1, Z21, Z87.890

    See the official tabular notes · Guidelines I.A.12.b

  • Code Also — related condition(1 note)

    Coding workflow: Review the related condition when both are documented and the instruction applies. A Code Also note does not fix sequencing; the order follows the circumstances of the encounter.

    See the official tabular notes · Guidelines I.A.17

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Don’t confuse Z78.0 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of Z78.0 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

  • N95.1— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of symptomatic menopausal state adds N95.1; it is not part of this code and both may be reported when both are documented.

    Full comparison: Z78.0 vs N95.1 →

  • Z21— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of asymptomatic human immunodeficiency virus [HIV] infection status adds Z21; it is not part of this code and both may be reported when both are documented.

    Full comparison: Z78.0 vs Z21 →

  • Z93— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of postprocedural status adds Z93; it is not part of this code and both may be reported when both are documented.

    Full comparison: Z78.0 vs Z93 →

  • Z99— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of postprocedural status adds Z99; it is not part of this code and both may be reported when both are documented.

    Full comparison: Z78.0 vs Z99 →

  • Z87.890— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of sex reassignment status adds Z87.890; it is not part of this code and both may be reported when both are documented.

    Full comparison: Z78.0 vs Z87.890 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Code Overview

Asymptomatic menopausal state is a billable ICD-10-CM diagnosis code (Z78.0).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Indexed Clinical Terms (3)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Official Coding Guidelines

Official source data — quoted verbatim from the CMS/NCHS Official Guidelines

Official source data — quoted verbatim from the CMS/NCHS Official Guidelines

Verbatim excerpts from the ICD-10-CM Official Guidelines for Coding and Reporting (CMS/NCHS) that govern this code.

Chapter 21: Factors influencing health status and contact with health services (Z00-Z99)

Z74.01 Bed confinement status Z76.82 Awaiting organ transplant status Z78 Other specified health status Code Z78.1, Physical restraint status, may be used when it is documented by the provider that a patient has been put in restraints during the current encounter. Please note that this code should not be reported when it is documented by the provider that a patient is temporarily restrained during a procedure. Z79 Long- term (current) drug therapy Codes from this category indicate a patient’s continuous use of a prescribed drug (including such things as aspirin therapy) for the long-term treatment of a condition or for prophylactic use. It is not for use for patients who have addictions to drugs. This subcategory is not for use of medications for detoxification or maintenance programs to prevent withdrawal symptoms (e.g., methadone maintenance for opiate dependence). Assign the appropriate code for the drug use, abuse, or dependence instead.

Verify Before Coding

  • Principal-diagnosis restriction. The Medicare Code Editor lists this code as unacceptable as a principal diagnosis: it describes a circumstance influencing health status rather than a current illness or injury being treated. It is valid as a secondary diagnosis.
  • Age-restricted: the Medicare Code Editor lists this as an adult (age 15-124) diagnosis; other ages are presumed incorrect.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder structured relationships — computed from published CMS and AHRQ datasets

Other codes that name Z78.0 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 1 Excludes1 note: N95.1 — Menopausal and female climacteric states.

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 1 Use Additional Code instruction: Z79.81 — Long term (current) use of agents affecting estrogen receptors and estrogen levels.

These codes instruct coders to additionally report this code when it applies.

MS-DRG Grouper Relationships (FY2027)

Potential MS-DRG participation — not a DRG assignment.

FY2027 MS-DRG: not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity for that release.

Named in the grouper logic of 1 MS-DRG: DRG 951 (MDC 23).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):FAC025 — Other specified status (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Principal diagnosis restriction (Medicare Code Editor)

Not acceptable as a principal diagnosis on an inpatient claim.

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Other specified status).

Z77.121 — Contact with and (suspected) exposure to harmful algae and algae toxins, Z77.122 — Contact with and (suspected) exposure to noise, Z77.123 — Contact with and (suspected) exposure to radon and other naturally occurring radiation, Z77.128 — Contact with and (suspected) exposure to other hazards in the physical environment, Z77.21 — Contact with and (suspected) exposure to potentially hazardous body fluids, Z77.22 — Contact with and (suspected) exposure to environmental tobacco smoke (acute) (chronic), Z77.29 — Contact with and (suspected) exposure to other hazardous substances, Z77.31 — Contact with and (suspected) exposure to Gulf War theater, Z77.39 — Contact with and (suspected) exposure to other war theater, Z77.9 — Other contact with and (suspected) exposures hazardous to health, Z78.1 — Physical restraint status, Z78.9 — Other specified health status, Z79.01 — Long term (current) use of anticoagulants, Z79.02 — Long term (current) use of antithrombotics/antiplatelets, Z79.1 — Long term (current) use of non-steroidal anti-inflammatories (NSAID), Z79.2 — Long term (current) use of antibiotics, Z79.3 — Long term (current) use of hormonal contraceptives, Z79.4 — Long term (current) use of insulin, Z79.51 — Long term (current) use of inhaled steroids, Z79.52 — Long term (current) use of systemic steroids, +232 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main terms “State”, “Menopause, menopausal”; these codes share that main term but sit in a different category of the Tabular List.

F41.0 — Panic disorder [episodic paroxysmal anxiety] (panic), F41.1 — Generalized anxiety disorder (anxiety), F42.2 — Mixed obsessional thoughts and acts (compulsive, mixed with obsessional thoughts), F42.8 — Other obsessive-compulsive disorder (compulsive), F43.0 — Acute stress reaction (crisis), F44.89 — Other dissociative and conversion disorders (confusional), F44.9 — Dissociative and conversion disorder, unspecified (dissociative), F48.1 — Depersonalization-derealization syndrome (neurotic, with depersonalization), F48.8 — Other specified nonpsychotic mental disorders (tension, specified NEC), F48.9 — Nonpsychotic mental disorder, unspecified (tension), F60.2 — Antisocial personality disorder (psychopathic), G83.5 — Locked-in state (locked-in), N92.4 — Excessive bleeding in the premenopausal period (bleeding), N95.1 — Menopausal and female climacteric states (menopausal, symptomatic), R40.3 — Persistent vegetative state (persistent vegetative), R45.1 — Restlessness and agitation (agitated), R45.7 — State of emotional shock and stress, unspecified (stress), Z33.1 — Pregnant state, incidental (pregnant, incidental), Z33.3 — Pregnant state, gestational carrier (pregnant, gestational carrier), Z73.0 — Burn-out (burn-out), +24 more

Contextual Map

Every relationship of Z78.0 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run Z78.0 with these 2 related codes in Claim Check

Hierarchy

Excludes2

Referenced by Excludes1 notes

Referenced by Use Additional Code instructions

Clinical classification (CCSR)

MS-DRG Grouper

MDC crossing

  • MDC 23 — Factors Influencing Health Status and Other Contacts with Health Services[MDC crossing]: “Factors Influencing Health Status and Other Contacts with Health Services — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 1,258 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2027

Index entries

  • Menopause, menopausal (asymptomatic) (state)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • State (of), climacteric, female[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • State (of), menopausal[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027

Nearest codes

Change history (3)

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2027 tabular list, index and tables, effective October 1, 2026 Release, file and checksum · Publisher’s page
Coding guidelines Official source data
ICD-10-CM Official Guidelines for Coding and Reporting (FY2027), quoted by section Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v44.0 (October 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v44 Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder structured relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "Z78.0 — Asymptomatic menopausal state." ICD-10-CM FY2027. https://medcoder.ai/icd10/code/z78.0-asymptomatic-menopausal-state

Change history

Changed in FY2027, the release in force: Excludes2 note added; Excludes2 note removed.

  • FY2027 — October 1, 2026
    Excludes2 note added
    sex reassignment status (Z87.890-)
    FY2027 changes
  • FY2027 — October 1, 2026
    Excludes2 note removed
    sex reassignment status (Z87.890)
    FY2027 changes
  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Asymptomatic menopausal state

Nearest Codes in This Family

Official ICD-10-CM classifications closest to Z78.0 in its code family, with their registry titles.

View all codes in the Z78 family