D59 ICD-10-CM Code: Acquired hemolytic anemia
Billing Status: NO. This is a clinician non-billable / parent hierarchy grouping in the ICD-10-CM system.
Coder workflow for D59
MedCoder structured workflow — derived from this code’s own official record
Before you code D59
- D59 is not reportable as written. Select the more specific code beneath it that the documentation supports. Codes are reported to the highest level of specificity the classification provides (Guidelines I.B.2).
ReviewD59.0, D59.1, D59.2, D59.3, D59.4, D59.5, D59.6, D59.8, D59.9
See the relationships section · Guide: How to choose an ICD-10-CM code →
Choose the right path
- Does the documentation support one of the more specific codes beneath D59?
Yes → Select that code and continue the checks below on its own page.
No → D59 cannot be reported as written; query for the specificity its subcategory needs.ReviewD59.0, D59.1, D59.2, D59.3, D59.4, D59.5, D59.6, D59.8, D59.9
Consider D59. Then confirm the code is valid for the date of service in the Verify section.
Documentation check
- The provider’s diagnostic statement
- Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.
Code Overview
MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.
Verify Before Coding
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.
Relationships & Classification
MedCoder structured relationships — computed from published CMS and AHRQ datasets
Other codes that name D59 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.
Referenced by 1 Excludes1 note: R71 — Abnormality of red blood cells.
These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.
Referenced by 23 Code First instructions across 3 chapters: I21.A1 — Myocardial infarction type 2, M90.5 — Osteonecrosis in diseases classified elsewhere, T36 — Poisoning by, adverse effect of and underdosing of systemic antibiotics, T36-T39 — Antibiotics & Anti-infectives (T36-T39), T36-T50 — Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (T36-T50), T37 — Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics, T38 — Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified, T39 — Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics, T40 — Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens], T40-T41 — Analgesics & Antipyretics (T40-T41), T41 — Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases, T42 — Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs, T42-T43 — Anticonvulsants & Psychotropics (T42-T43), T43 — Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified, T44 — Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system, T44-T46 — Cardiovascular & Gastrointestinal (T44-T46), T45 — Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified, T46 — Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system, T47 — Poisoning by, adverse effect of and underdosing of agents primarily affecting the gastrointestinal system, T47-T50 — Hormones & Systemic Agents (T47-T50), +3 more.
Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.
Contextual Map
Every relationship of D59 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Run D59 with these 9 related codes in Claim Check
Hierarchy
- D50-D89 — Chapter 3: Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89) (D50-D89)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D55-D59 — Hemolytic anemias[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Referenced by Excludes1 notes
- R71 — Abnormality of red blood cells[Excludes1]: “anemias (D50-D64)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Referenced by Code First instructions (23)
- I21.A1 — Myocardial infarction type 2[Code First]: “anemia (D50.0-D64.9)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- M90.5 — Osteonecrosis in diseases classified elsewhere[Code First]: “hemoglobinopathy (D50-D64)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T36 — Poisoning by, adverse effect of and underdosing of systemic antibiotics[Code First]: “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T36-T39 — Antibiotics & Anti-infectives (T36-T39)[Code First]: “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T36-T50 — Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (T36-T50)[Code First]: “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T37 — Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics[Code First]: “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T38 — Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified[Code First]: “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T39 — Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics[Code First]: “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- and 15 more
Nearest codes (18)
- D59.0 — Drug-induced autoimmune hemolytic anemia[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D59.1 — Other autoimmune hemolytic anemias[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D59.10 — Autoimmune hemolytic anemia, unspecified[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D59.11 — Warm autoimmune hemolytic anemia[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D59.12 — Cold autoimmune hemolytic anemia[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D59.13 — Mixed type autoimmune hemolytic anemia[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D59.19 — Other autoimmune hemolytic anemia[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D59.2 — Drug-induced nonautoimmune hemolytic anemia[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- and 10 more
Change history
- FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016
Common coding questions
Can D59 be billed directly?
No. D59 (Acquired hemolytic anemia) is a non-billable ICD-10-CM category code. A more specific billable subcode must be selected based on clinical documentation.
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, title, tabular notes and index terms Official source data
- CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
- Claim edits Official source data
- CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder structured relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates
Cite this page
Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.
MedCoder.ai. "D59 — Acquired hemolytic anemia." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/d59-acquired-hemolytic-anemia
Change history
- FY2016 — October 1, 2015In the code set at ICD-10-CM adoptionAcquired hemolytic anemia
No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to D59 in its code family, with their registry titles.
- D59.0 — Drug-induced autoimmune hemolytic anemia
- D59.1 — Other autoimmune hemolytic anemias
- D59.10 — Autoimmune hemolytic anemia, unspecified
- D59.11 — Warm autoimmune hemolytic anemia
- D59.12 — Cold autoimmune hemolytic anemia
- D59.13 — Mixed type autoimmune hemolytic anemia
- D59.19 — Other autoimmune hemolytic anemia
- D59.2 — Drug-induced nonautoimmune hemolytic anemia
- D59.3 — Hemolytic-uremic syndrome
- D59.30 — Hemolytic-uremic syndrome, unspecified
- D59.31 — Infection-associated hemolytic-uremic syndrome
- D59.32 — Hereditary hemolytic-uremic syndrome
- D59.39 — Other hemolytic-uremic syndrome
- D59.4 — Other nonautoimmune hemolytic anemias
- D59.5 — Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]
- D59.6 — Hemoglobinuria due to hemolysis from other external causes
- D59.8 — Other acquired hemolytic anemias
- D59.9 — Acquired hemolytic anemia, unspecified