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I49.49 ICD-10-CM Code: Other premature depolarization

Compare with another codeCheck this code on a claim

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Tabular directives
4 inclusion terms · 5 Excludes2 · 3 code-first instructions

Billable · FY2027A valid, specific ICD-10-CM code, reportable for dates of service in FY2027.

What you need to know

Source: CMS/NCHS Official ICD-10-CM tabular notes, quoted. From the CMS/NCHS tabular list for the release in force. A note the category or block publishes applies to this code too; the Instructions section marks which is which.

Code firstSequence the underlying condition before this code
  • cardiac arrhythmia complicating:
  • abortion or ectopic or molar pregnancy (O00-O07, O08.8)
  • obstetric surgery and procedures (O75.4)
Excludes2Not included here; may be reported together
  • bradycardia NOS (R00.1)
  • neonatal dysrhythmia (P29.1-)
  • sinoatrial bradycardia (R00.1)
  • sinus bradycardia (R00.1)

+1 more in Instructions

IncludesWhat this code covers
  • Ectopic beats
  • Extrasystoles
  • Extrasystolic arrhythmias
  • Premature contractions

Most relevant related codes MedCoder-derived

Read off the official notes above and this code’s own position in the tabular list. Which to report is a documentation question; Compare shows the two side by side.

CompareCheck ClaimView Related Codes

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v44, Appendix B.

  • MS-DRG 308 — CARDIAC ARRHYTHMIA AND CONDUCTION DISORDERS WITH MCC (MDC 05)
  • MS-DRG 309 — CARDIAC ARRHYTHMIA AND CONDUCTION DISORDERS WITH CC (MDC 05)
  • MS-DRG 310 — CARDIAC ARRHYTHMIA AND CONDUCTION DISORDERS WITHOUT CC/MCC (MDC 05)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for I49.49 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2027Effective: October 1, 2026

Trace:FY2027 changesChange historyRelease, file and checksum

Notes without a marker are published on I49.49 itself; “inherited from” names the category or block whose note applies here.

Inclusion Terms

Alternative terms the tabular list files under this code.

  • Ectopic beats
  • Extrasystoles
  • Extrasystolic arrhythmias
  • Premature contractions

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Source: inherited from I49

Code First

Underlying conditions that must be sequenced before this code.

  • cardiac arrhythmia complicating:
  • abortion or ectopic or molar pregnancy (O00-O07, O08.8)
  • obstetric surgery and procedures (O75.4)

Source: inherited from I49

Coder workflow for I49.49

MedCoder structured workflow — derived from this code’s own official record

Before you code I49.49

  1. “Other” (NEC) means the condition is specified in the record but no dedicated code captures it. Confirm the documented form is not one a sibling code names before settling on I49.49; if the record states no specifics at all, the unspecified sibling applies instead. “Other” codes are for documented conditions the classification gives no specific code; “unspecified” codes are for records lacking the detail (Guidelines I.A.9.a, I.A.9.b).

    See the relationships section · Guide: Other vs unspecified (NEC vs NOS) →

Choose the right path

  1. Is the underlying (etiologic) condition the Code First note names documented?
    Yes → Sequence the underlying condition first, then I49.49.
    No → Continue; do not add an underlying condition the record does not document.

    ReviewO08.8, O75.4

Consider I49.49. Then confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
The underlying (etiologic) condition
Named in the Code First note; sequenced before this code when documented (Guidelines I.A.13).
Any detail beyond this code’s title
What the record states that a more specific sibling code would capture — or its absence, which itself supports the unspecified code.

Official instructions as workflow

  • Excludes2 — not part of I49.49(5 notes)

    Coding workflow: The conditions named in this note are not included in I49.49. When the record documents both, both may be reported; the note is a boundary, not a prohibition.

    CompareR00.1, P29.1

    See the official tabular notes · Guidelines I.A.12.b

  • Code First — sequencing check(3 notes)

    Coding workflow: Check whether the underlying or etiologic condition the note names is documented. When it is, sequence it before I49.49. Do not add an underlying condition the record does not document.

    ReviewO08.8, O75.4

    See the official tabular notes · Guidelines I.A.13

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Documentation: The underlying condition the Code First note names is documented alongside this condition.

Coding question: How are the two sequenced?

Path: Review the Code First note.

Reason: The underlying condition is sequenced first and the manifestation follows (Guidelines I.A.13).

ReviewO08.8, O75.4

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Don’t confuse I49.49 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of I49.49 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

  • I49.40— Specificity relationship (Review)

    Overlapping diagnoses in the same category.

    Overlapping codes in the same category — the documentation decides which is the more specific fit.

    What moves you there: A record that documents no more than “Unspecified premature depolarization” takes I49.40; specificity in the record moves it back here.

    Full comparison: I49.49 vs I49.40 →

  • R00.1— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of bradycardia NOS adds R00.1; it is not part of this code and both may be reported when both are documented.

    Full comparison: I49.49 vs R00.1 →

  • P29.1— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of neonatal dysrhythmia adds P29.1; it is not part of this code and both may be reported when both are documented.

    Full comparison: I49.49 vs P29.1 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Coding context

Guidelines, coding notes, decision aids, relationships (with MS-DRG and CCSR classification), hierarchy, HCC, coverage and the context map: what a coder reaches for after the core. Each section names whether it is official source data, a MedCoder-derived relationship or MedCoder editorial.

Code Overview

Other premature depolarization is a billable ICD-10-CM diagnosis code (I49.49).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Verify Before Coding

  • No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder-derived relationships — computed from published CMS and AHRQ datasets

Other codes that name I49.49 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 1 Excludes2 note: R00 — Abnormalities of heart beat (via I49.-).

These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.

Referenced by 1 Code Also instruction: M35.81 — Multisystem inflammatory syndrome (via I49.-).

These codes suggest coding this condition alongside when both are present.

MS-DRG Grouper Relationships (FY2027)

Potential MS-DRG participation — not a DRG assignment.

FY2027 MS-DRG: not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity for that release.

Named in the grouper logic of 3 MS-DRGs: DRG 308 (MDC 05), DRG 309 (MDC 05), DRG 310 (MDC 05).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):CIR017 — Cardiac dysrhythmias (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Cardiac dysrhythmias).

I47.29 — Other ventricular tachycardia, I47.9 — Paroxysmal tachycardia, unspecified, I48.0 — Paroxysmal atrial fibrillation, I48.1 — Persistent atrial fibrillation, I48.11 — Longstanding persistent atrial fibrillation, I48.19 — Other persistent atrial fibrillation, I48.2 — Chronic atrial fibrillation, I48.20 — Chronic atrial fibrillation, unspecified, I48.21 — Permanent atrial fibrillation, I48.3 — Typical atrial flutter, I48.4 — Atypical atrial flutter, I48.91 — Unspecified atrial fibrillation, I48.92 — Unspecified atrial flutter, I49.1 — Atrial premature depolarization, I49.2 — Junctional premature depolarization, I49.3 — Ventricular premature depolarization, I49.40 — Unspecified premature depolarization, I49.5 — Sick sinus syndrome, I49.8 — Other specified cardiac arrhythmias, I49.9 — Cardiac arrhythmia, unspecified, +8 more

Same Index main term, other category

The ICD-10-CM Index to Diseases and Injuries files this code under the main terms “Contraction, contracture, contracted”, “Arrhythmia”, “Premature”, …; these codes share that main term but sit in a different category of the Tabular List.

E28.319 — Asymptomatic premature menopause (menopause), E30.1 — Precocious puberty (puberty), E30.8 — Other disorders of puberty (thelarche), E34.2 — Ectopic hormone secretion, not elsewhere classified (hormone secretion NEC), E34.8 — Other specified endocrine disorders (aging), F44.4 — Conversion disorder with motor symptom or deficit (hysterical), F45.8 — Other somatoform disorders (psychogenic), F52.4 — Premature ejaculation (ejaculation), I45.9 — Conduction disorder, unspecified (block), I47.0 — Re-entry ventricular arrhythmia (ventricular re-entry), J98.09 — Other diseases of bronchus, not elsewhere classified (bronchial), K31.89 — Other diseases of stomach and duodenum (stomach), K59.89 — Other specified functional intestinal disorders (anus), K82.0 — Obstruction of gallbladder (gallbladder), K83.8 — Other specified diseases of biliary tract (bile duct), M24.50 — Contracture, unspecified joint (joint), M24.51 — Contracture, shoulder (joint, shoulder), M24.52 — Contracture, elbow (joint, elbow), M24.53 — Contracture, wrist (joint, wrist), M24.54 — Contracture, hand (joint, hand joint), +83 more

Lab tests where this diagnosis supports Medicare coverage (NCD)

Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.

Iron Panel, Prothrombin Time Test and INR (PT/INR)

Contextual Map

Every relationship of I49.49 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run I49.49 with these 2 related codes in Claim Check

Hierarchy

Referenced by Excludes2 notes

Referenced by Code Also instructions

Clinical classification (CCSR)

MS-DRG Grouper

MDC crossing

  • MDC 05 — Diseases and Disorders of the Circulatory System[MDC crossing]: “Diseases and Disorders of the Circulatory System — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 15,708 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2027

Index entries (10)

  • Arrhythmia (auricle)(cardiac)(juvenile)(nodal)(reflex)(supraventricular)(transitory)(ventricle), extrasystolic[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Beat (s), ectopic[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Beat (s), escaped, heart[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Contraction, contracture, contracted (s), premature, auriculoventricular[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Contraction, contracture, contracted (s), premature, heart[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Depolarization, premature, specified NEC[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Ectopic, ectopia (congenital), beats[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • Extrasystoles (supraventricular)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2027
  • and 2 more

Nearest codes (15)

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Reference

Index terms and tables, published questions and FAQ, every source behind this page with its release and checksum, the date-of-service check and the complete change history.

Indexed Clinical Terms (10)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2027 tabular list, index and tables, effective October 1, 2026 Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v44.0 (October 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v44 Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder-derived relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder editorial explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 20, 2026 · All releases and sources

Labels on this page: Official source data · MedCoder-derived relationship · MedCoder editorial explanation. How to read the labels · All data sources and release dates · CMS coding rules

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "I49.49 — Other premature depolarization." ICD-10-CM FY2027. https://medcoder.ai/icd10/code/i49.49-other-premature-depolarization

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Other premature depolarization

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027, and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to I49.49 in its code family, with their registry titles.

View all codes in the I49 family