P61.1 ICD-10-CM Code: Polycythemia neonatorum
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Coding at a Glance
- Tabular directives
- 6 Excludes1
Inpatient Payment Groups (MS-DRG)
Potential MS-DRG participation — not a DRG assignment.
MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v43, Appendix B.
- MS-DRG 794 — NEONATE WITH OTHER SIGNIFICANT PROBLEMS (MDC 15)
A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.
Coding instructions
Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for P61.1 in the official ICD-10-CM tabular list, quoted as published.
Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2026Effective: October 1, 2025
Notes without a marker are published on P61.1 itself; “inherited from” names the category or block whose note applies here.
Excludes1 — Not Coded Here
Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).
- transient hypogammaglobulinemia of infancy (D80.7) inherited from P61Compare P61.1 vs D80.7 →
- congenital stenosis and stricture of bile ducts (Q44.3) inherited from P50-P61Compare P61.1 vs Q44.3 →
- Crigler-Najjar syndrome (E80.5) inherited from P50-P61Compare P61.1 vs E80.5 →
- Dubin-Johnson syndrome (E80.6) inherited from P50-P61Compare P61.1 vs E80.6 →
- Gilbert syndrome (E80.4) inherited from P50-P61Compare P61.1 vs E80.4 →
- hereditary hemolytic anemias (D55-D58) inherited from P50-P61Compare P61.1 vs D55 →
Coder workflow for P61.1
MedCoder structured workflow — derived from this code’s own official record
Before you code P61.1
- Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with P61.1. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).
Choose the right path
- Does the documentation support a condition named in P61.1’s Excludes1 note?
Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
No → Continue.
Consider P61.1. Then confirm the code is valid for the date of service in the Verify section.
Documentation check
- The provider’s diagnostic statement
- Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
Official instructions as workflow
Excludes1 — check before selecting P61.1(6 notes)
Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with P61.1: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.
CompareD80.7, Q44.3, E80.5, E80.6, E80.4
See the official tabular notes · Guidelines I.A.12.a
Coding decision scenarios
Pattern scenarios for this code’s structure — decision rules, not clinical cases
Documentation: Both the condition P61.1 describes and a condition named in its Excludes1 note are documented for the same encounter.
Coding question: Can both codes be reported?
Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.
Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).
Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.
Code Overview
MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.
Indexed Clinical Terms (5)
Official source data — entries quoted as published, in the Index’s own lookup phrasing
Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.
Verify Before Coding
- No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.
Relationships & Classification
MedCoder structured relationships — computed from published CMS and AHRQ datasets
Other codes that name P61.1 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.
Referenced by 2 Excludes1 notes across 2 chapters: D75.1 — Secondary polycythemia, R71 — Abnormality of red blood cells.
These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.
Referenced by 10 Excludes2 notes: R70 — Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity (via P61.-), R70-R79 — Abnormal findings on examination of blood, without diagnosis (R70-R79) (via P61.-), R71 — Abnormality of red blood cells (via P61.-), R73 — Elevated blood glucose level (via P61.-), R74 — Abnormal serum enzyme levels (via P61.-), R75 — Inconclusive laboratory evidence of human immunodeficiency virus [HIV] (via P61.-), R76 — Other abnormal immunological findings in serum (via P61.-), R77 — Other abnormalities of plasma proteins (via P61.-), R78 — Findings of drugs and other substances, not normally found in blood (via P61.-), R79 — Other abnormal findings of blood chemistry (via P61.-).
These codes’ tabular lists name this diagnosis as distinct — both may be reported when both are documented.
MS-DRG Grouper Relationships (FY2026)
Potential MS-DRG participation — not a DRG assignment.
FY2026 MS-DRG: not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity for that release.
Named in the grouper logic of 1 MS-DRG: DRG 794 (MDC 15).
From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.
Clinical classification (AHRQ CCSR):PNL011 — Hemorrhagic and hematologic disorders of newborn (default).
Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.
Related Codes
Same clinical category (CCSR)
AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Hemorrhagic and hematologic disorders of newborn).
P52.9 — Intracranial (nontraumatic) hemorrhage of newborn, unspecified, P53 — Hemorrhagic disease of newborn, P54.0 — Neonatal hematemesis, P54.1 — Neonatal melena, P54.2 — Neonatal rectal hemorrhage, P54.3 — Other neonatal gastrointestinal hemorrhage, P54.4 — Neonatal adrenal hemorrhage, P54.5 — Neonatal cutaneous hemorrhage, P54.6 — Neonatal vaginal hemorrhage, P54.8 — Other specified neonatal hemorrhages, P54.9 — Neonatal hemorrhage, unspecified, P60 — Disseminated intravascular coagulation of newborn, P61.0 — Transient neonatal thrombocytopenia, P61.2 — Anemia of prematurity, P61.3 — Congenital anemia from fetal blood loss, P61.4 — Other congenital anemias, not elsewhere classified, P61.5 — Transient neonatal neutropenia, P61.6 — Other transient neonatal disorders of coagulation, P61.8 — Other specified perinatal hematological disorders, P61.9 — Perinatal hematological disorder, unspecified, +20 more
Same Index main term, other category
The ICD-10-CM Index to Diseases and Injuries files this code under the main terms “Plethora”, “Polycythemia”; these codes share that main term but sit in a different category of the Tabular List.
D45 — Polycythemia vera (vera), D75.0 — Familial erythrocytosis (benign), D75.1 — Secondary polycythemia, R23.2 — Flushing
Lab tests where this diagnosis supports Medicare coverage (NCD)
Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.
Partial Thromboplastin Time (PTT) Test, Prothrombin Time Test and INR (PT/INR)
Contextual Map
Every relationship of P61.1 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Run P61.1 with these 9 related codes in Claim Check
Hierarchy
- P00-P96 — Chapter 16: Certain Conditions Originating in the Perinatal Period (P00-P96) (P00-P96)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- P50-P61 — Hemorrhagic and hematological disorders of newborn[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Referenced by Excludes1 notes
- D75.1 — Secondary polycythemia[Excludes1]: “polycythemia neonatorum (P61.1)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R71 — Abnormality of red blood cells[Excludes1]: “polycythemia neonatorum (P61.1)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Referenced by Excludes2 notes (10)
- R70 — Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity[Excludes2](via P61.-): “hemorrhagic and hematological disorders of newborn (P50-P61)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R70-R79 — Abnormal findings on examination of blood, without diagnosis (R70-R79)[Excludes2](via P61.-): “hemorrhagic and hematological disorders of newborn (P50-P61)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R71 — Abnormality of red blood cells[Excludes2](via P61.-): “hemorrhagic and hematological disorders of newborn (P50-P61)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R73 — Elevated blood glucose level[Excludes2](via P61.-): “hemorrhagic and hematological disorders of newborn (P50-P61)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R74 — Abnormal serum enzyme levels[Excludes2](via P61.-): “hemorrhagic and hematological disorders of newborn (P50-P61)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R75 — Inconclusive laboratory evidence of human immunodeficiency virus [HIV][Excludes2](via P61.-): “hemorrhagic and hematological disorders of newborn (P50-P61)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R76 — Other abnormal immunological findings in serum[Excludes2](via P61.-): “hemorrhagic and hematological disorders of newborn (P50-P61)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- R77 — Other abnormalities of plasma proteins[Excludes2](via P61.-): “hemorrhagic and hematological disorders of newborn (P50-P61)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- and 2 more
Clinical classification (CCSR)
- PNL011 — Hemorrhagic and hematologic disorders of newborn[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)
MS-DRG Grouper
- DRG 794 — NEONATE WITH OTHER SIGNIFICANT PROBLEMS[MS-DRG]: “NEONATE WITH OTHER SIGNIFICANT PROBLEMS (MDC 15)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2026
MDC crossing
- MDC 15 — Newborns and Other Neonates with Conditions Originating in Perinatal Period[MDC crossing]: “Newborns and Other Neonates with Conditions Originating in Perinatal Period — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”— CMS MS-DRG Definitions Manual · FY2026
Index entries
- Plethora, newborn[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
- Polycythemia (secondary), due to, donor twin[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
- Polycythemia (secondary), due to, maternal-fetal transfusion[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
- Polycythemia (secondary), neonatorum[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
- Syndrome, hypertransfusion, newborn[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
Nearest codes (9)
- P61 — Other perinatal hematological disorders[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- P61.0 — Transient neonatal thrombocytopenia[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- P61.2 — Anemia of prematurity[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- P61.3 — Congenital anemia from fetal blood loss[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- P61.4 — Other congenital anemias, not elsewhere classified[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- P61.5 — Transient neonatal neutropenia[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- P61.6 — Other transient neonatal disorders of coagulation[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- P61.8 — Other specified perinatal hematological disorders[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- and 1 more
Change history
- FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, title, tabular notes and index terms Official source data
- CMS/CDC ICD-10-CM FY2026 tabular list, index and tables, effective October 1, 2025 Release, file and checksum · Publisher’s page
- Claim edits Official source data
- CMS Definitions of Medicare Code Edits — v43.1 (April 2026) Release, file and checksum · Publisher’s page
- Inpatient payment groups Official source data
- CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v43 Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder structured relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates
Cite this page
Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.
MedCoder.ai. "P61.1 — Polycythemia neonatorum." ICD-10-CM FY2026. https://medcoder.ai/icd10/code/p61.1-polycythemia-neonatorum
Change history
- FY2016 — October 1, 2015In the code set at ICD-10-CM adoptionPolycythemia neonatorum
No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027 (effective October 1, 2026), and none are recorded for this code. Note changes are tracked from FY2027 only.
Nearest Codes in This Family
Official ICD-10-CM classifications closest to P61.1 in its code family, with their registry titles.
- P61 — Other perinatal hematological disorders
- P61.0 — Transient neonatal thrombocytopenia
- P61.2 — Anemia of prematurity
- P61.3 — Congenital anemia from fetal blood loss
- P61.4 — Other congenital anemias, not elsewhere classified
- P61.5 — Transient neonatal neutropenia
- P61.6 — Other transient neonatal disorders of coagulation
- P61.8 — Other specified perinatal hematological disorders
- P61.9 — Perinatal hematological disorder, unspecified