D75.84 ICD-10-CM Code: Other platelet-activating anti-PF4 disorders
Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.
Coding at a Glance
- Tabular directives
- 3 inclusion terms · 6 Excludes2 · 1 use-additional code
- Risk adjustment
- CMS-HCC V28: 1 category · CMS-HCC V22 category 48
Inpatient Payment Groups (MS-DRG)
Potential MS-DRG participation — not a DRG assignment.
MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v44, Appendix B.
- MS-DRG 791 — PREMATURITY WITH MAJOR PROBLEMS (MDC 15)
- MS-DRG 793 — FULL TERM NEONATE WITH MAJOR PROBLEMS (MDC 15)
- MS-DRG 813 — COAGULATION DISORDERS (MDC 16)
A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.
Risk Adjustment (CMS-HCC)
Payment categories this diagnosis maps to under CMS-HCC V28, payment year 2026.
- HCC 112 — Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions
Other models: CMS-HCC V22 HCC 48
Risk scores depend on the enrollee's full accepted diagnosis set and segment; a category mapping alone does not determine payment.
Coding instructions
Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for D75.84 in the official ICD-10-CM tabular list, quoted as published.
Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2027Effective: October 1, 2026
Notes without a marker are published on D75.84 itself; “inherited from” names the category or block whose note applies here.
Inclusion Terms
Alternative terms the tabular list files under this code.
- Spontaneous heparin-induced thrombocytopenia syndrome (without heparin exposure)
- Thrombosis with thrombocytopenia syndrome
- Vaccine-induced thrombotic thrombocytopenia
Excludes2 — Not Included Here
Conditions not covered by this code, but which may be reported alongside it when both are present.
- acute lymphadenitis (L04.-) Compare D75.84 vs L04 →
- chronic lymphadenitis (I88.1) Compare D75.84 vs I88.1 →
- enlarged lymph nodes (R59.-) Compare D75.84 vs R59 →
- hypergammaglobulinemia NOS (D89.2) Compare D75.84 vs D89.2 →
- lymphadenitis NOS (I88.9) Compare D75.84 vs I88.9 →
- mesenteric lymphadenitis (acute) (chronic) (I88.0) Compare D75.84 vs I88.0 →
Source: inherited from D75
Use Additional Code
Supplementary codes the tabular list directs you to add.
- Use additional code, if applicable, for adverse effect of other viral vaccine (T50.B95-)
Coder workflow for D75.84
MedCoder structured workflow — derived from this code’s own official record
Before you code D75.84
- “Other” (NEC) means the condition is specified in the record but no dedicated code captures it. Confirm the documented form is not one a sibling code names before settling on D75.84; if the record states no specifics at all, the unspecified sibling applies instead. “Other” codes are for documented conditions the classification gives no specific code; “unspecified” codes are for records lacking the detail (Guidelines I.A.9.a, I.A.9.b).
See the relationships section · Guide: Other vs unspecified (NEC vs NOS) →
Documentation check
- The provider’s diagnostic statement
- Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
- The conditions the Use Additional Code note names
- Reported with this code when documented; a conditional instruction (“if applicable”, “if known”) applies only when the record supports it.
- Any detail beyond this code’s title
- What the record states that a more specific sibling code would capture — or its absence, which itself supports the unspecified code.
Official instructions as workflow
Excludes2 — not part of D75.84(6 notes)
Coding workflow: The conditions named in this note are not included in D75.84. When the record documents both, both may be reported; the note is a boundary, not a prohibition.
CompareL04, I88.1, R59, D89.2, I88.9, I88.0
See the official tabular notes · Guidelines I.A.12.b
Use Additional Code — after identifying D75.84(1 note)
Coding workflow: Check whether the documentation supports the additional code(s) the note names, and report them with D75.84 when it does. Where the instruction is conditional (“if applicable”, “if known”), it applies only when the record documents the condition.
ReviewT50.B95
See the official tabular notes · Guidelines I.A.13
Coding decision scenarios
Pattern scenarios for this code’s structure — decision rules, not clinical cases
Documentation: A condition the Use Additional Code note names is documented.
Coding question: Is a second code reported with D75.84?
Path: Review the Use Additional Code note and the code it names.
Reason: The additional code is reported when the record documents the condition; a conditional instruction applies only when its condition is met (Guidelines I.A.13).
ReviewT50.B95
Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.
Code Overview
MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.
Indexed Clinical Terms (4)
Official source data — entries quoted as published, in the Index’s own lookup phrasing
Clinical term phrases from the official ICD-10-CM Index to Diseases and Injuries that map to this code. These are alphabetic-index entries shown as the Index writes them — lookup phrasing, not necessarily the wording of a final diagnosis.
Official Coding Guidelines
No excerpt in the ICD-10-CM Official Guidelines names this code specifically. Its chapter carries only this chapter-wide note:
Chapter 3: Disease of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Reserved for future guideline expansion
Verify Before Coding
- No Medicare Code Editor or MS-DRG Definitions Manual restrictions apply to this code.
From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.
Relationships & Classification
MedCoder structured relationships — computed from published CMS and AHRQ datasets
Other codes that name D75.84 or its code family, from the CMS ICD-10-CM tabular instructional notes. Tabular-note edges are stored at the code family level that carries each note.
Referenced by 21 Code First instructions: T36 — Poisoning by, adverse effect of and underdosing of systemic antibiotics (via D75.-), T36-T39 — Antibiotics & Anti-infectives (T36-T39) (via D75.-), T36-T50 — Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (T36-T50) (via D75.-), T37 — Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics (via D75.-), T38 — Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified (via D75.-), T39 — Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics (via D75.-), T40 — Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens] (via D75.-), T40-T41 — Analgesics & Antipyretics (T40-T41) (via D75.-), T41 — Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases (via D75.-), T42 — Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs (via D75.-), T42-T43 — Anticonvulsants & Psychotropics (T42-T43) (via D75.-), T43 — Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified (via D75.-), T44 — Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system (via D75.-), T44-T46 — Cardiovascular & Gastrointestinal (T44-T46) (via D75.-), T45 — Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified (via D75.-), T46 — Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system (via D75.-), T47 — Poisoning by, adverse effect of and underdosing of agents primarily affecting the gastrointestinal system (via D75.-), T47-T50 — Hormones & Systemic Agents (T47-T50) (via D75.-), T48 — Poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system (via D75.-), T49 — Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs (via D75.-), +1 more.
Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.
MS-DRG Grouper Relationships (FY2027)
Potential MS-DRG participation — not a DRG assignment.
FY2027 MS-DRG: not on the CMS CC/MCC list — as a secondary diagnosis this code does not change MS-DRG severity for that release.
Named in the grouper logic of 3 MS-DRGs: DRG 791 (MDC 15), DRG 793 (MDC 15), DRG 813 (MDC 16).
From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.
Clinical classification (AHRQ CCSR):BLD006 — Coagulation and hemorrhagic disorders (default).
Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.
Related Codes
Same CMS-HCC risk category (V28)
CMS maps these diagnoses to the same Hierarchical Condition Category (Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions) for risk-adjusted payment.
D68.00 — Von Willebrand disease, unspecified, D68.01 — Von Willebrand disease, type 1, D68.020 — Von Willebrand disease, type 2A, D68.021 — Von Willebrand disease, type 2B, D68.022 — Von Willebrand disease, type 2M, D68.023 — Von Willebrand disease, type 2N, D68.029 — Von Willebrand disease, type 2, unspecified, D68.03 — Von Willebrand disease, type 3, D68.04 — Acquired von Willebrand disease, D68.09 — Other von Willebrand disease, D68.1 — Hereditary factor XI deficiency, D68.2 — Hereditary deficiency of other clotting factors, D68.311 — Acquired hemophilia, D69.1 — Qualitative platelet defects, D69.3 — Immune thrombocytopenic purpura, D69.41 — Evans syndrome, D69.42 — Congenital and hereditary thrombocytopenia purpura, D69.49 — Other primary thrombocytopenia, M31.10 — Thrombotic microangiopathy, unspecified, M31.19 — Other thrombotic microangiopathy
Related risk categories
These categories interact through CMS's HCC hierarchy — one can suppress the other's risk-adjustment weight when both are present on a claim.
Hemophilia, Male
Same clinical category (CCSR)
AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Coagulation and hemorrhagic disorders).
D69.1 — Qualitative platelet defects, D69.2 — Other nonthrombocytopenic purpura, D69.3 — Immune thrombocytopenic purpura, D69.41 — Evans syndrome, D69.42 — Congenital and hereditary thrombocytopenia purpura, D69.49 — Other primary thrombocytopenia, D69.51 — Posttransfusion purpura, D69.59 — Other secondary thrombocytopenia, D69.6 — Thrombocytopenia, unspecified, D69.8 — Other specified hemorrhagic conditions, D69.9 — Hemorrhagic condition, unspecified, D75.82 — Heparin induced thrombocytopenia (HIT), D75.821 — Non-immune heparin-induced thrombocytopenia, D75.822 — Immune-mediated heparin-induced thrombocytopenia, D75.828 — Other heparin-induced thrombocytopenia syndrome, D75.829 — Heparin-induced thrombocytopenia, unspecified, D75.838 — Other thrombocytosis, D75.839 — Thrombocytosis, unspecified, M36.2 — Hemophilic arthropathy, O72.3 — Postpartum coagulation defects, +31 more
Same Index main term, other category
The ICD-10-CM Index to Diseases and Injuries files this code under the main term “Thrombocytopenia, thrombocytopenic”; these codes share that main term but sit in a different category of the Tabular List.
D69.3 — Immune thrombocytopenic purpura (essential), D69.42 — Congenital and hereditary thrombocytopenia purpura (hereditary), D69.49 — Other primary thrombocytopenia (primary NEC), D69.59 — Other secondary thrombocytopenia (secondary), D69.6 — Thrombocytopenia, unspecified, O72.3 — Postpartum coagulation defects (puerperal, postpartum), P61.0 — Transient neonatal thrombocytopenia (transient neonatal), Q87.2 — Congenital malformation syndromes predominantly involving limbs (with absent radius)
Lab tests where this diagnosis supports Medicare coverage (NCD)
Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.
Contextual Map
Every relationship of D75.84 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.
Run D75.84 with these 9 related codes in Claim Check
Hierarchy
- D50-D89 — Chapter 3: Diseases of the Blood and Blood-forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89) (D50-D89)[Hierarchy]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
Use Additional Code
- T50.B95 — Adverse effect of other viral vaccines[Use Additional Code]: “code, if applicable, for adverse effect of other viral vaccine (T50.B95-)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
Referenced by Code First instructions (21)
- T36 — Poisoning by, adverse effect of and underdosing of systemic antibiotics[Code First](via D75.-): “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T36-T39 — Antibiotics & Anti-infectives (T36-T39)[Code First](via D75.-): “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T36-T50 — Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (T36-T50)[Code First](via D75.-): “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T37 — Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics[Code First](via D75.-): “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T38 — Poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified[Code First](via D75.-): “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T39 — Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics[Code First](via D75.-): “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T40 — Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens][Code First](via D75.-): “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- T40-T41 — Analgesics & Antipyretics (T40-T41)[Code First](via D75.-): “blood disorders (D56-D76)”— CMS ICD-10-CM tabular instructional notes · icd10cm-fy2026
- and 13 more
Clinical classification (CCSR)
- BLD006 — Coagulation and hemorrhagic disorders[CCSR]— AHRQ CCSR for ICD-10-CM Diagnoses (HCUP)
Risk adjustment (CMS-HCC)
- HCC 112 — Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions [CMS-HCC]— CMS-HCC V28 · 2026
MS-DRG Grouper
- DRG 791 — PREMATURITY WITH MAJOR PROBLEMS[MS-DRG]: “PREMATURITY WITH MAJOR PROBLEMS (MDC 15)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- DRG 793 — FULL TERM NEONATE WITH MAJOR PROBLEMS[MS-DRG]: “FULL TERM NEONATE WITH MAJOR PROBLEMS (MDC 15)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
- DRG 813 — COAGULATION DISORDERS[MS-DRG]: “COAGULATION DISORDERS (MDC 16)”— CMS MS-DRG Definitions Manual (Appendix B) · FY2027
MDC crossing
- MDC 15 — Newborns and Other Neonates with Conditions Originating in Perinatal Period[MDC crossing]: “Newborns and Other Neonates with Conditions Originating in Perinatal Period — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs.”— CMS MS-DRG Definitions Manual · FY2027
- MDC 16 — Diseases and Disorders of Blood, Blood Forming Organs and Immunologic Disorders[MDC crossing]: “Diseases and Disorders of Blood, Blood Forming Organs and Immunologic Disorders — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 1,615 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2027
Index entries
- Disorder (of), platelet-activating anti-PF4, specified NEC[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
- Syndrome, thrombosis with thrombocytopenia[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
- Thrombocytopenia, thrombocytopenic, heparin induced (HIT), syndrome, spontaneous (without heparin exposure)[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
- Thrombocytopenia, thrombocytopenic, vaccine-induced thrombotic[Index term]— CMS ICD-10-CM Index to Diseases and Injuries · icd10cm-fy2026
Nearest codes (16)
- D75 — Other and unspecified diseases of blood and blood-forming organs[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D75.0 — Familial erythrocytosis[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D75.1 — Secondary polycythemia[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D75.8 — Other specified diseases of blood and blood-forming organs[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D75.81 — Myelofibrosis[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D75.82 — Heparin induced thrombocytopenia (HIT)[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D75.821 — Non-immune heparin-induced thrombocytopenia[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- D75.822 — Immune-mediated heparin-induced thrombocytopenia[Sibling]— CMS ICD-10-CM tabular structure · icd10cm-fy2026
- and 8 more
Change history
- FY2023 — Added to the code set[Change history]— CMS release files (code change ledger) · icd10cm-fy2023
Sources for this page
Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.
- Code, title, tabular notes and index terms Official source data
- CMS/CDC ICD-10-CM FY2027 tabular list, index and tables, effective October 1, 2026 Release, file and checksum · Publisher’s page
- Coding guidelines Official source data
- ICD-10-CM Official Guidelines for Coding and Reporting (FY2027), quoted by section Release, file and checksum · Publisher’s page
- Claim edits Official source data
- CMS Definitions of Medicare Code Edits — v44.0 (October 2026) Release, file and checksum · Publisher’s page
- Inpatient payment groups Official source data
- CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v44 Release, file and checksum · Publisher’s page
- Risk adjustment Official source data
- 2026 Mid-Year Final ICD-10 Mappings + Model Software (cms.gov/files/zip/2026-midyear-final-icd-10-mappings.zip, 2026-midyear-final-model-software.zip) — CMS-HCC V28, PY2026 mid-year final release Release, file and checksum · Publisher’s page
- Change history and date-of-service validity Official source data
- CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
- Comparisons, relationships and the contextual map MedCoder structured relationship
- Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
- Summary and FAQ answers MedCoder explanation
- Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.
Labels on this page: Official source data · MedCoder structured relationship · MedCoder explanation. How to read the labels · All data sources and release dates
Cite this page
Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.
MedCoder.ai. "D75.84 — Other platelet-activating anti-PF4 disorders." ICD-10-CM FY2027. https://medcoder.ai/icd10/code/d75.84-other-platelet-activating-anti-pf4-disorders
Change history
- FY2023 — October 1, 2022Added to the code setOther platelet-activating anti-PF4 disordersFY2023 changes
Nearest Codes in This Family
Official ICD-10-CM classifications closest to D75.84 in its code family, with their registry titles.
- D75.821 — Non-immune heparin-induced thrombocytopenia
- D75.822 — Immune-mediated heparin-induced thrombocytopenia
- D75.828 — Other heparin-induced thrombocytopenia syndrome
- D75.829 — Heparin-induced thrombocytopenia, unspecified
- D75.83 — Thrombocytosis
- D75.838 — Other thrombocytosis
- D75.839 — Thrombocytosis, unspecified
- D75.89 — Other specified diseases of blood and blood-forming organs
- D75.9 — Disease of blood and blood-forming organs, unspecified
- D75.A — Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia