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C49.9 ICD-10-CM Code: Malignant neoplasm of connective and soft tissue, unspecified

Compare with another code for C49.9Check this code on a claim

Billing Status: YES. This is a valid, specific, and billable ICD-10-CM reference.

Coding at a Glance

Tabular directives
10 inclusion terms · 5 Excludes1 · 7 Excludes2
Risk adjustment
CMS-HCC V28: 1 category · CMS-HCC V22 category 10 · RxHCC V08 category 22

Billable · FY2027A valid, specific ICD-10-CM code, reportable for dates of service in FY2027.

What you need to know

Source: CMS/NCHS Official ICD-10-CM tabular notes, quoted. From the CMS/NCHS tabular list for the release in force. A note the category or block publishes applies to this code too, and is marked with where it comes from.

Excludes1from C49Not reported with this code unless documented as unrelated

+1 more in Instructions

Excludes2from C49Not included here; may be reported together
  • Kaposi's sarcoma of soft tissue (C46.1)
  • malignant neoplasm of heart (C38.0)
  • malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
  • malignant neoplasm of peritoneum (C48.2)

+3 more in Instructions

Includesfrom C49What C49 covers
  • malignant neoplasm of blood vessel
  • malignant neoplasm of bursa
  • malignant neoplasm of cartilage
  • malignant neoplasm of fascia

+6 more in Instructions

Where it sits Source: CMS/NCHS

Under:Chapter 2: NeoplasmsC00-C96 Malignant neoplasmsC00-C75 Malignant neoplasms, stated or presumed to be primary (of specified sites), and certain specified histologies, except neuroendocrine, and of lymphoid, hematopoietic and related tissueC45-C49 Malignant neoplasms of mesothelial and soft tissueC49 Malignant neoplasm of other connective and soft tissue

Most relevant related codes MedCoder-derived

Read off the official notes above and this code’s own position in the tabular list. Which to report is a documentation question; Compare shows the two side by side.

CompareCheck ClaimView Related Codes

Inpatient Payment Groups (MS-DRG)

Potential MS-DRG participation — not a DRG assignment.

MS-DRGs this diagnosis helps define, as principal or secondary, per the CMS ICD-10-CM/PCS MS-DRG Definitions Manual v44, Appendix B.

  • MS-DRG 542 — PATHOLOGICAL FRACTURES AND MUSCULOSKELETAL AND CONNECTIVE TISSUE MALIGNANCY WITH MCC (MDC 08)
  • MS-DRG 543 — PATHOLOGICAL FRACTURES AND MUSCULOSKELETAL AND CONNECTIVE TISSUE MALIGNANCY WITH CC (MDC 08)
  • MS-DRG 544 — PATHOLOGICAL FRACTURES AND MUSCULOSKELETAL AND CONNECTIVE TISSUE MALIGNANCY WITHOUT CC/MCC (MDC 08)

A diagnosis appearing in a group's logic does not by itself determine the DRG assigned to a stay; the grouper uses the full claim.

Risk Adjustment (CMS-HCC)

Payment categories this diagnosis maps to under CMS-HCC V28, payment year 2026.

  • HCC 21 — Lymphoma and Other Cancers (supersedes HCC 22, HCC 23)

Other models: CMS-HCC V22 HCC 10 · RxHCC V08 HCC 22

Risk scores depend on the enrollee's full accepted diagnosis set and segment; a category mapping alone does not determine payment.

Coding instructions

Official Tabular Instructional Notes: the inclusion, exclusion and sequencing notes published for C49.9 in the official ICD-10-CM tabular list, quoted as published.

Source: CMS/CDC — ICD-10-CM Tabular ListRelease: FY2027Effective: October 1, 2026

Trace:FY2027 changesChange historyRelease, file and checksum

Notes without a marker are published on C49.9 itself; “inherited from” names the category or block whose note applies here.

Includes

Conditions the official ICD-10-CM tabular list includes under this code.

  • malignant neoplasm of blood vessel
  • malignant neoplasm of bursa
  • malignant neoplasm of cartilage
  • malignant neoplasm of fascia
  • malignant neoplasm of fat
  • malignant neoplasm of ligament, except uterine
  • malignant neoplasm of lymphatic vessel
  • malignant neoplasm of muscle
  • malignant neoplasm of synovia
  • malignant neoplasm of tendon (sheath)

Source: inherited from C49

Excludes1 — Not Coded Here

Conditions generally not reported together with this code (Excludes1) -- an error unless the two conditions are documented as unrelated to each other (ICD-10-CM Official Guidelines, Section I.A.12.a).

Source: inherited from C49

Excludes2 — Not Included Here

Conditions not covered by this code, but which may be reported alongside it when both are present.

Source: inherited from C49

Coder workflow for C49.9

MedCoder structured workflow — derived from this code’s own official record

Before you code C49.9

  1. Unspecified does not mean incorrect. When the record gives no greater specificity, C49.9 may be the appropriate code. Check the record for detail that supports a more specific sibling. An unspecified code is for records that do not provide the detail a more specific code needs; a query, not an assumption, is the route to specificity (Guidelines I.A.9.b, I.B.18).

    ReviewC49.0, C49.1, C49.2, C49.3, C49.4, C49.5, C49.8, C49.A

    See the relationships section · Guide: Other vs unspecified (NEC vs NOS) →

  2. Confirm the documented site and behavior (this code’s block classifies malignant neoplasms), whether the site is primary or secondary, and whether the malignancy is current or a personal history: a previously excised malignancy with no further treatment and no evidence of disease is history, not current disease. Verify the site against the Table of Neoplasms. Neoplasm chapter guidelines (Guidelines I.C.2.a, I.C.2.d, I.C.2.m).

    See the Table of Neoplasms entries · Guide: Active cancer vs history of cancer →

  3. Check the Excludes1 note: if the documentation supports a condition named there, do not simply proceed with C49.9. Excludes1 conditions are not reported together with this code unless the record shows they are unrelated (Guidelines I.A.12.a).

    See the official tabular notes

Choose the right path

  1. Does the record document the detail a more specific sibling code needs?
    Yes → Review the specific siblings in this subcategory.
    No → Continue — C49.9 is appropriate when the documentation goes no further.

    ReviewC49.0, C49.1, C49.2, C49.3, C49.4, C49.5, C49.8, C49.A

  2. Does the documentation support a condition named in C49.9’s Excludes1 note?
    Yes → Do not simply proceed: review the excluded code. Both are reported only when the record shows the two conditions are unrelated.
    No → Continue.

    ReviewC32.3, C30.0, C50

Consider C49.9. Then confirm the code is valid for the date of service in the Verify section.

Documentation check

The provider’s diagnostic statement
Codes are assigned from the provider’s documented diagnosis, not from clinical criteria, test values or a medication list (Guidelines I.A.19).
Anatomical site
At the most specific level the record states; a site the classification separates cannot be assumed from a procedure or a measurement.
Behavior and current-versus-history status
Malignant, in situ, benign or uncertain; primary or secondary; current disease or personal history (Guidelines I.C.2.m).
Any detail beyond this code’s title
What the record states that a more specific code would capture — or its absence, which itself supports the unspecified code.

Official instructions as workflow

  • Excludes1 — check before selecting C49.9(5 notes)

    Coding workflow: If the documentation supports a condition named in this note, do not simply proceed with C49.9: the two are not reported together. The one exception is when the record shows the two conditions are unrelated to each other.

    CompareC32.3, C30.0, C50

    See the official tabular notes · Guidelines I.A.12.a

  • Excludes2 — not part of C49.9(7 notes)

    Coding workflow: The conditions named in this note are not included in C49.9. When the record documents both, both may be reported; the note is a boundary, not a prohibition.

    CompareC46.1, C38.0, C47, C48.2, C48.0, C57.3

    See the official tabular notes · Guidelines I.A.12.b

Coding decision scenarios

Pattern scenarios for this code’s structure — decision rules, not clinical cases

Documentation: The provider documents the condition in the terms of this code’s title and records no further detail.

Coding question: Is a more specific sibling code supportable?

Path: Review the specific siblings in this subcategory and what each requires the record to state.

Reason: A more specific code needs documentation of the distinguishing element; without it the unspecified code is appropriate, and a provider query is the route to specificity (Guidelines I.A.9.b, I.B.18).

ReviewC49.0, C49.1, C49.2, C49.3, C49.4, C49.5, C49.8, C49.A

Documentation: Both the condition C49.9 describes and a condition named in its Excludes1 note are documented for the same encounter.

Coding question: Can both codes be reported?

Path: Review the Excludes1 note and the excluded code, and look for a provider statement on whether the two conditions are related.

Reason: Excludes1 means the two are not coded together; the exception is when the record shows the conditions are unrelated to each other (Guidelines I.A.12.a).

ReviewC32.3, C30.0, C50

Every row is derived from this code’s own record — its title, tabular notes, 7th-character family and same-category siblings — with fixed MedCoder wording; nothing is inferred about a patient. The official notes and guideline text are in the sections each row links to, and they control.

Don’t confuse C49.9 with…

MedCoder analysis — pairs from this code’s official notes, distinctions written by MedCoder

The codes most likely to be picked instead of C49.9 — named in its own official notes, or sharing its laterality or encounter family — with what separates them and which documentation moves the case. Each links to the full comparison.

  • C40— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of articular moves the case to C40; the two are not reported together unless documented as unrelated.

    Full comparison: C49.9 vs C40 →

  • C41— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of articular moves the case to C41; the two are not reported together unless documented as unrelated.

    Full comparison: C49.9 vs C41 →

  • C32.3— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of larynx moves the case to C32.3; the two are not reported together unless documented as unrelated.

    Full comparison: C49.9 vs C32.3 →

  • C30.0— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of nose moves the case to C30.0; the two are not reported together unless documented as unrelated.

    Full comparison: C49.9 vs C30.0 →

  • C50— Excludes1 conflict (Excludes1 — generally not reported together)

    Not coded here — the tabular list excludes this pair for the same encounter.

    Not reported together with this code, except where the two conditions are documented as unrelated.

    What moves you there: Documentation of malignant neoplasm of connective tissue of breast moves the case to C50; the two are not reported together unless documented as unrelated.

    Full comparison: C49.9 vs C50 →

  • C46.1— Excludes2 relationship (Informational)

    Distinct conditions — both may be reported.

    A distinct condition — both may be reported when both are documented.

    What moves you there: Documentation of Kaposi's sarcoma of soft tissue adds C46.1; it is not part of this code and both may be reported when both are documented.

    Full comparison: C49.9 vs C46.1 →

Relationships are read from this code's own official notes, its laterality siblings and its encounter family; the wording of each distinction is MedCoder editorial, and the documentation named in each “what moves you there” line is the official note phrase or sibling title itself. Source: CMS ICD-10-CM tabular instructional notes; ICD-10-CM Official Guidelines, Section I.A.12.a.

Coding context

Guidelines, coding notes, decision aids, relationships (with MS-DRG and CCSR classification), hierarchy, HCC, coverage and the context map: what a coder reaches for after the core. Each section names whether it is official source data, a MedCoder-derived relationship or MedCoder editorial.

Code Overview

Malignant neoplasm of connective and soft tissue, unspecified is a billable ICD-10-CM diagnosis code (C49.9).

MedCoder summary Summary composed by MedCoder from this code's official ICD-10-CM record. The tabular instructional notes themselves appear verbatim below.

Verify Before Coding

  • CC as a secondary diagnosis (FY2027). Can raise the stay's MS-DRG severity tier.

From the code registry, the Medicare Code Editor, and the MS-DRG Definitions Manual. Check it against a full claim in Claim Check.

Relationships & Classification

MedCoder-derived relationships — computed from published CMS and AHRQ datasets

Other codes that name C49.9 or its code family, from the CMS ICD-10-CM tabular instructional notes and the CMS Table of Neoplasms. Tabular-note edges are stored at the code family level that carries each note.

Referenced by 3 Excludes1 notes: C40 — Malignant neoplasm of bone and articular cartilage of limbs (via C49.-), C40-C41 — Malignant neoplasms of bone and articular cartilage (C40-C41) (via C49.-), C41 — Malignant neoplasm of bone and articular cartilage of other and unspecified sites (via C49.-).

These codes’ tabular lists mark this diagnosis as mutually exclusive — not reported together unless the conditions are documented as unrelated.

Referenced by 1 Code First instruction: M63 — Disorders of muscle in diseases classified elsewhere (via C49.-).

Each of these codes carries a Code First note naming this condition — when that code is reported, THIS code is sequenced first, ahead of it.

Referenced by 4 Same-site neoplasm codes: C79.89 — Secondary malignant neoplasm of other specified sitesCompare C49.9 vs C79.89 →, D21.9 — Benign neoplasm of connective and other soft tissue, unspecifiedCompare C49.9 vs D21.9 →, D48.1 — Neoplasm of uncertain behavior of connective and other soft tissueCompare C49.9 vs D48.1 →, D49.2 — Neoplasm of unspecified behavior of bone, soft tissue, and skinCompare C49.9 vs D49.2 →.

These codes represent related neoplasm behaviors affecting the same anatomic site.

MS-DRG Grouper Relationships (FY2027)

Potential MS-DRG participation — not a DRG assignment.

FY2027 MS-DRG: CC — Complication or Comorbidity. Reported as a secondary diagnosis, this code raises the stay's MS-DRG severity tier — except when the principal diagnosis is one of 2 clinically related codes on its CMS exclusion list.

Named in the grouper logic of 3 MS-DRGs: DRG 542 (MDC 08), DRG 543 (MDC 08), DRG 544 (MDC 08).

From the CMS MS-DRG Definitions Manual (Appendices B and C). Actual DRG assignment depends on the complete claim.

Clinical classification (AHRQ CCSR):NEO024 — Sarcoma (default).

Clinical Classifications Software Refined (CCSR) for ICD-10-CM Diagnoses. Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality.

Related Codes

Same clinical process (MS-DRG)

Acts as CC — raises the severity of other admissions. CMS groups these diagnoses into one MS-DRG principal-diagnosis exclusion process — a CC/MCC on this list never raises severity when the principal diagnosis is also on it.

Z51.0 — Encounter for antineoplastic radiation therapy

Same CMS-HCC risk category (V28)

CMS maps these diagnoses to the same Hierarchical Condition Category (Lymphoma and Other Cancers) for risk-adjusted payment.

C49.10 — Malignant neoplasm of connective and soft tissue of unspecified upper limb, including shoulder, C49.11 — Malignant neoplasm of connective and soft tissue of right upper limb, including shoulder, C49.12 — Malignant neoplasm of connective and soft tissue of left upper limb, including shoulder, C49.20 — Malignant neoplasm of connective and soft tissue of unspecified lower limb, including hip, C49.21 — Malignant neoplasm of connective and soft tissue of right lower limb, including hip, C49.22 — Malignant neoplasm of connective and soft tissue of left lower limb, including hip, C49.3 — Malignant neoplasm of connective and soft tissue of thorax, C49.5 — Malignant neoplasm of connective and soft tissue of pelvis, C49.6 — Malignant neoplasm of connective and soft tissue of trunk, unspecified, C49.8 — Malignant neoplasm of overlapping sites of connective and soft tissue, C4A.0 — Merkel cell carcinoma of lip, C4A.10 — Merkel cell carcinoma of unspecified eyelid, including canthus, C4A.111 — Merkel cell carcinoma of right upper eyelid, including canthus, C4A.112 — Merkel cell carcinoma of right lower eyelid, including canthus, C4A.121 — Merkel cell carcinoma of left upper eyelid, including canthus, C4A.122 — Merkel cell carcinoma of left lower eyelid, including canthus, C4A.20 — Merkel cell carcinoma of unspecified ear and external auricular canal, C4A.21 — Merkel cell carcinoma of right ear and external auricular canal, C4A.22 — Merkel cell carcinoma of left ear and external auricular canal, C4A.30 — Merkel cell carcinoma of unspecified part of face, +442 more

Related risk categories

These categories interact through CMS's HCC hierarchy — one can suppress the other's risk-adjustment weight when both are present on a claim.

Cancer Metastatic to Lung, Liver, Brain, and Other Organs; Acute Myeloid Leukemia Except Promyelocytic, Cancer Metastatic to Bone, Other and Unspecified Metastatic Cancer; Acute Leukemia Except Myeloid, Myelodysplastic Syndromes, Multiple Myeloma, and Other Cancers, Lung and Other Severe Cancers, Bladder, Colorectal, and Other Cancers, Prostate, Breast, and Other Cancers and Tumors

Same clinical category (CCSR)

AHRQ's Clinical Classifications Software groups these diagnoses under the same clinical category (Sarcoma).

C46.50 — Kaposi's sarcoma of unspecified lung, C46.51 — Kaposi's sarcoma of right lung, C46.52 — Kaposi's sarcoma of left lung, C46.7 — Kaposi's sarcoma of other sites, C46.9 — Kaposi's sarcoma, unspecified, C49.0 — Malignant neoplasm of connective and soft tissue of head, face and neck, C49.10 — Malignant neoplasm of connective and soft tissue of unspecified upper limb, including shoulder, C49.11 — Malignant neoplasm of connective and soft tissue of right upper limb, including shoulder, C49.12 — Malignant neoplasm of connective and soft tissue of left upper limb, including shoulder, C49.20 — Malignant neoplasm of connective and soft tissue of unspecified lower limb, including hip, C49.21 — Malignant neoplasm of connective and soft tissue of right lower limb, including hip, C49.22 — Malignant neoplasm of connective and soft tissue of left lower limb, including hip, C49.3 — Malignant neoplasm of connective and soft tissue of thorax, C49.4 — Malignant neoplasm of connective and soft tissue of abdomen, C49.5 — Malignant neoplasm of connective and soft tissue of pelvis, C49.6 — Malignant neoplasm of connective and soft tissue of trunk, unspecified, C49.8 — Malignant neoplasm of overlapping sites of connective and soft tissue, C96.22 — Mast cell sarcoma, C96.4 — Sarcoma of dendritic cells (accessory cells), C96.A — Histiocytic sarcoma, +5 more

Lab tests where this diagnosis supports Medicare coverage (NCD)

Medicare's National Coverage Determination (NCD) program lists this diagnosis as medical justification for these lab tests.

Gamma-glutamyl Transferase (GGT) Test, Iron Panel

Contextual Map

Every relationship of C49.9 in one view: hierarchy, official tabular instructions in both directions, clinical classification, risk adjustment, MS-DRG participation, index terms and change history — each edge carrying the CMS source it derives from.

Run C49.9 with these 4 related codes in Claim Check

Hierarchy

Same site

Referenced by Excludes1 notes

Referenced by Code First instructions

Referenced by Same-site neoplasm codes

Clinical classification (CCSR)

Risk adjustment (CMS-HCC)

  • HCC 21 — Lymphoma and Other Cancers [CMS-HCC]: “Lymphoma and Other Cancers — supersedes HCC 22 (Bladder, Colorectal, and Other Cancers), HCC 23 (Prostate, Breast, and Other Cancers and Tumors)”— CMS-HCC V28 · 2026

MS-DRG Grouper

MDC crossing

  • MDC 08 — Diseases and Disorders of the Musculoskeletal System and Connective Tissue[MDC crossing]: “Diseases and Disorders of the Musculoskeletal System and Connective Tissue — the grouper's crossing between diagnoses and procedures: a principal diagnosis sets the MDC, and same-MDC procedures move the stay to its surgical DRGs. 18,439 same-MDC procedures group here; browse them on the MDC page.”— CMS MS-DRG Definitions Manual · FY2027

Neoplasm sites

  • Neoplasm, neoplastic, aponeurosis — Neoplasm, neoplastic, aponeurosis — Malignant, Primary [Neoplasm table]: “Neoplasm, neoplastic, aponeurosis (Malignant, Primary)”— CMS Table of Neoplasms · icd10cm-fy2027
  • Neoplasm, neoplastic, connective tissue NEC — Neoplasm, neoplastic, connective tissue NEC — Malignant, Primary [Neoplasm table]: “Neoplasm, neoplastic, connective tissue NEC (Malignant, Primary)”— CMS Table of Neoplasms · icd10cm-fy2027
  • Neoplasm, neoplastic, connective tissue NEC, extremity — Neoplasm, neoplastic, connective tissue NEC, extremity — Malignant, Primary [Neoplasm table]: “Neoplasm, neoplastic, connective tissue NEC, extremity (Malignant, Primary)”— CMS Table of Neoplasms · icd10cm-fy2027
  • Neoplasm, neoplastic, connective tissue NEC, limb NEC — Neoplasm, neoplastic, connective tissue NEC, limb NEC — Malignant, Primary [Neoplasm table]: “Neoplasm, neoplastic, connective tissue NEC, limb NEC (Malignant, Primary)”— CMS Table of Neoplasms · icd10cm-fy2027
  • Neoplasm, neoplastic, lymph, lymphatic channel NEC — Neoplasm, neoplastic, lymph, lymphatic channel NEC — Malignant, Primary [Neoplasm table]: “Neoplasm, neoplastic, lymph, lymphatic channel NEC (Malignant, Primary)”— CMS Table of Neoplasms · icd10cm-fy2027
  • Neoplasm, neoplastic, lymph, lymphatic channel NEC, vessel — Neoplasm, neoplastic, lymph, lymphatic channel NEC, vessel — Malignant, Primary [Neoplasm table]: “Neoplasm, neoplastic, lymph, lymphatic channel NEC, vessel (Malignant, Primary)”— CMS Table of Neoplasms · icd10cm-fy2027

Nearest codes (23)

Change history

  • FY2016 — In the code set at ICD-10-CM adoption [Change history]— CMS release files (code change ledger) · icd10cm-fy2016

Reference

Index terms and tables, published questions and FAQ, every source behind this page with its release and checksum, the date-of-service check and the complete change history.

Neoplasm Table Sites (6)

Official source data — entries quoted as published, in the Index’s own lookup phrasing

Anatomical sites from the official ICD-10-CM Table of Neoplasms that map to this code, with the matching behavior column.

  • Neoplasm, neoplastic, aponeurosis — Malignant, Primary
  • Neoplasm, neoplastic, connective tissue NEC — Malignant, Primary
  • Neoplasm, neoplastic, connective tissue NEC, extremity — Malignant, Primary
  • Neoplasm, neoplastic, connective tissue NEC, limb NEC — Malignant, Primary
  • Neoplasm, neoplastic, lymph, lymphatic channel NEC — Malignant, Primary
  • Neoplasm, neoplastic, lymph, lymphatic channel NEC, vessel — Malignant, Primary

Sources for this page

Codes, titles, notes, index terms and mappings on this page are transcribed from the datasets below. Relationships MedCoder computed and text MedCoder wrote are labelled where they appear.

Code, title, tabular notes and index terms Official source data
CMS/CDC ICD-10-CM FY2027 tabular list, index and tables, effective October 1, 2026 Release, file and checksum · Publisher’s page
Claim edits Official source data
CMS Definitions of Medicare Code Edits — v44.0 (October 2026) Release, file and checksum · Publisher’s page
Inpatient payment groups Official source data
CMS MS-DRG Definitions Manual (incl. Appendix B diagnosis index, Appendix C CC/MCC list, Appendix E procedure index) and IPPS Final Rule tables — v44 Release, file and checksum · Publisher’s page
Risk adjustment Official source data
2026 Mid-Year Final ICD-10 Mappings + Model Software (cms.gov/files/zip/2026-midyear-final-icd-10-mappings.zip, 2026-midyear-final-model-software.zip) — CMS-HCC V28, PY2026 mid-year final release Release, file and checksum · Publisher’s page
Change history and date-of-service validity Official source data
CMS ICD-10-CM release addenda, ingested release by release into the change ledger Release, file and checksum · Publisher’s page
Comparisons, relationships and the contextual map MedCoder-derived relationship
Computed by MedCoder from the tabular notes and tables above; every derived relationship is marked as derived where it appears
Summary and FAQ answers MedCoder editorial explanation
Written by MedCoder to explain the sources above: drafted with AI assistance, checked by a person against the release files, and labelled as MedCoder text where it appears. Not official text.

Current data releases:ICD-10-CM FY2027 · ICD-10-PCS FY2027 · HCPCS October 2026 · MS-DRG v44 · Medicare Code Editor v44.0 · NCCI PTP Q4 2026 · MUE Q4 2026 · NCD code lists 2026-01 · LCD export September 28, 2026 · All releases and sources

Labels on this page: Official source data · MedCoder-derived relationship · MedCoder editorial explanation. How to read the labels · All data sources and release dates · CMS coding rules

Cite this page

Reference this page in a research guide, syllabus or article. The release is included because code content changes each year.

MedCoder.ai. "C49.9 — Malignant neoplasm of connective and soft tissue, unspecified." ICD-10-CM FY2027. https://medcoder.ai/icd10/code/c49.9-malignant-neoplasm-of-connective-and-soft-tissue-unspecified

Change history

  • FY2016 — October 1, 2015
    In the code set at ICD-10-CM adoption
    Malignant neoplasm of connective and soft tissue, unspecified

No changes since FY2016 — additions, deletions, description changes and billable-status changes are tracked through FY2027, and none are recorded for this code. Note changes are tracked from FY2027 only.

Nearest Codes in This Family

Official ICD-10-CM classifications closest to C49.9 in its code family, with their registry titles.

View all codes in the C49 family